Intracellular delivery of nanogel-quantum dot hybrid nanoparticles into human periodontal ligament cells.

Tomoe Fukui, Hiroaki Kobayashi, Urara Hasegawa, Toshiyuki Nagasawa, Kazunari Akiyoshi, Isao Ishikawa

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

Nanogels of cholesterol-bearing pullulan modified with amino-groups (CHPNH(2)) were utilized as a career to introduce quantum dots (QDs) into periodontal ligament (PDL) cells. Nanogel-QD effectively labeled PDL cells over 3 weeks. These results indicate that CHPNH(2)nanogels have a potential as a research tool in the studies of intracellular delivery system.

Original languageEnglish (US)
Pages (from-to)131-135
Number of pages5
JournalDrug Metabolism Letters
Volume1
Issue number2
DOIs
StatePublished - Apr 2007

All Science Journal Classification (ASJC) codes

  • Pharmaceutical Science
  • Clinical Biochemistry
  • Biochemistry, medical
  • Pharmacology (medical)

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