Intramolecular thermal cyclotrimerization of an acyclic triyne: An uncatalyzed process

Martin G. Kociolek, Richard P. Johnson

Research output: Contribution to journalArticle

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Abstract

Flash vapor pyrolysis of 1,6,11-dodecatriyne at 500 to 600 °C and 0.01 torr affords 1,2,3,6,7,8-Hexahydro-[as]-indacene and dehydro derivatives. An uncatalyzed and highly exothermic two-step cycloaromatization mechanism is suggested. This proceeds through initial formation of a 1,4-diradical.

Original languageEnglish (US)
Pages (from-to)4141-4144
Number of pages4
JournalTetrahedron Letters
Volume40
Issue number22
DOIs
Publication statusPublished - May 28 1999

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All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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