Intranasal administration of a pseudomonas lipopolysaccharide vaccine in cystic fibrosis patients

Robert E. Wood, James E. Pennington, Herbert Reynolds

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

A purified lipopolysaccharide Pseudomonas aeruginosa vaccine was administered via intranasal spray to cystic fibrosis patients in an attempt to induce development of local antibody without the side effects associated with parenteral administration of the vaccine. Although slight increases in serum antibody titers were noted, there was no appreciable change in specific antibody levels in parotid saliva or sputum following intranasal administration of the vaccine.

Original languageEnglish (US)
Pages (from-to)367-369
Number of pages3
JournalPediatric Infectious Disease
Volume2
Issue number5
DOIs
StatePublished - Jan 1 1983

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Pseudomonas Vaccines
Intranasal Administration
Cystic Fibrosis
Lipopolysaccharides
Antibodies
Vaccines
Sputum
Saliva
Pseudomonas aeruginosa
Serum

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Microbiology (medical)

Cite this

Wood, Robert E. ; Pennington, James E. ; Reynolds, Herbert. / Intranasal administration of a pseudomonas lipopolysaccharide vaccine in cystic fibrosis patients. In: Pediatric Infectious Disease. 1983 ; Vol. 2, No. 5. pp. 367-369.
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Intranasal administration of a pseudomonas lipopolysaccharide vaccine in cystic fibrosis patients. / Wood, Robert E.; Pennington, James E.; Reynolds, Herbert.

In: Pediatric Infectious Disease, Vol. 2, No. 5, 01.01.1983, p. 367-369.

Research output: Contribution to journalArticle

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