Intranasal administration of a pseudomonas lipopolysaccharide vaccine in cystic fibrosis patients

Robert E. Wood, James E. Pennington, Herbert Y. Reynolds

Research output: Contribution to journalArticle

18 Scopus citations

Abstract

A purified lipopolysaccharide Pseudomonas aeruginosa vaccine was administered via intranasal spray to cystic fibrosis patients in an attempt to induce development of local antibody without the side effects associated with parenteral administration of the vaccine. Although slight increases in serum antibody titers were noted, there was no appreciable change in specific antibody levels in parotid saliva or sputum following intranasal administration of the vaccine.

Original languageEnglish (US)
Pages (from-to)367-369
Number of pages3
JournalPediatric Infectious Disease
Volume2
Issue number5
DOIs
StatePublished - Jan 1 1983

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Microbiology (medical)

Fingerprint Dive into the research topics of 'Intranasal administration of a pseudomonas lipopolysaccharide vaccine in cystic fibrosis patients'. Together they form a unique fingerprint.

  • Cite this