Intraoperative assessment of acute hemodynamic changes after partial left ventriculectomy

Steven Koenig, Mohammad Shafie, Anthony Pearson, Mary Ann Laureano, Pat Cerrito, Daniel Ewert, Mark Schroeder, Robert D. Dowling

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Partial left ventriculectomy (PLV) has been introduced as an alternative surgical therapy for patients with end-stage dilated cardiomyopathy. The physiological benefits of PLV are relatively unknown. Therefore, the objective of this study was to determine the acute effects of PLY by measuring cardiac function before and after PLV. Aortic and left ventricular pressures and aortic flow were measured in eight patients. Continuous, beat- to-beat data were recorded and compared pre-PLV and post-PLV with and without inferior vena cava (IVC) occlusions. PLV increased cardiac output (0.93 ± 0.5, p = 0.01) as a result of increased stroke volume (5.12 ± 4.24, p = 0.06) and heart rate (14.5 ± 8.44, p = 0.02). Contractility (±dP/dt, 240.33 ± 74.28, p = 0.001) and external work (650.8 ± 320.4, p = 0.01) were also improved. Left ventricular end-diastolic elastance (0.15 ± 0.14, p = 0.10) nearly doubled after PLV. Our results indicated an improved cardiac function as measured by increased cardiac output, stroke volume, ejection fraction (EF), and contractility.

Original languageEnglish (US)
Pages (from-to)152-156
Number of pages5
JournalJournal of Cardiac Surgery
Volume14
Issue number2
DOIs
StatePublished - 1999

All Science Journal Classification (ASJC) codes

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

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