TY - JOUR
T1 - Intravitreal Corticosteroids in the Management of Diabetic Macular Edema
AU - Schwartz, Stephen G.
AU - Flynn, Harry W.
AU - Scott, Ingrid U.
N1 - Funding Information:
This study was partially supported by NIH Center Core Grant P30EY014801, an Unrestricted Grant from Research to Prevent Blindness (New York, NY), and the Department of Defense (DOD Grant #W81XWH-09-1-0675).
Publisher Copyright:
© 2013, Springer Science + Business Media New York.
PY - 2013/9/1
Y1 - 2013/9/1
N2 - Diabetic macular edema (DME) remains an important cause of visual loss worldwide. Corticosteroids have a role in the treatment of some patients with advanced or recurrent DME. The best studied steroids for this indication are triamcinolone acetonide, dexamethasone, and fluocinolone acetonide. All steroids are associated with risks of cataract and intraocular pressure elevation. In addition, intravitreal injection of any medication is associated with such risks as infectious endophthalmitis, which has led to the investigation of various extended-release steroid implants. At this time, no steroid is approved by the United States Food and Drug Administration for the treatment of DME.
AB - Diabetic macular edema (DME) remains an important cause of visual loss worldwide. Corticosteroids have a role in the treatment of some patients with advanced or recurrent DME. The best studied steroids for this indication are triamcinolone acetonide, dexamethasone, and fluocinolone acetonide. All steroids are associated with risks of cataract and intraocular pressure elevation. In addition, intravitreal injection of any medication is associated with such risks as infectious endophthalmitis, which has led to the investigation of various extended-release steroid implants. At this time, no steroid is approved by the United States Food and Drug Administration for the treatment of DME.
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U2 - 10.1007/s40135-013-0015-3
DO - 10.1007/s40135-013-0015-3
M3 - Article
AN - SCOPUS:84906806780
VL - 1
SP - 144
EP - 149
JO - Current Ophthalmology Reports
JF - Current Ophthalmology Reports
SN - 2167-4868
IS - 3
ER -