Investigation of the pK_a of the nucleophilic O2' of the hairpin ribozyme

Chemical Compounds

• Nucleophilicity 61%
• Deprotonation 48%
• Nucleophile 45%
• Ground State 41%
• Molecular Dynamics 38%
• Amine 33%
• Metal Ion 32%
• Alcohol 31%
• Ion 20%

Physics & Astronomy

• positioning 52%
• nucleophiles 45%
• organizing 32%
• amines 30%
• attack 28%
• metal ions 28%
• alcohols 27%
• interactions 20%
• molecular dynamics 18%
• ground state 17%
• estimates 15%
• ions 12%

Engineering & Materials Science

• Catalytic RNA 100%
• Nucleophiles 21%
• Deprotonation 20%
• Ground state 15%
• Acidification 15%
• Metal ions 15%
• RNA 12%
• Amines 12%
• Molecular dynamics 11%
• Alcohols 11%
• Ions 9%