Investigation of the stereochemistry of intermolecular conjugate additions of nucleophiles to acyclic nitrosoalkenes

Jason A. Witek, Steven M. Weinreb

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Michael-type conjugate additions of γ-chiral aldehyde-derived acyclic nitrosoalkenes have been explored using a series of carbon and hetero nucleophiles. In all cases examined, these reactions are stereoselective, leading exclusively to the anti products.(Figure Presented)

Original languageEnglish (US)
Pages (from-to)1258-1260
Number of pages3
JournalOrganic Letters
Volume13
Issue number5
DOIs
StatePublished - Mar 4 2011

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Nucleophiles
Stereochemistry
nucleophiles
stereochemistry
aldehydes
Aldehydes
Carbon
carbon
products

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Cite this

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abstract = "Michael-type conjugate additions of γ-chiral aldehyde-derived acyclic nitrosoalkenes have been explored using a series of carbon and hetero nucleophiles. In all cases examined, these reactions are stereoselective, leading exclusively to the anti products.(Figure Presented)",
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Investigation of the stereochemistry of intermolecular conjugate additions of nucleophiles to acyclic nitrosoalkenes. / Witek, Jason A.; Weinreb, Steven M.

In: Organic Letters, Vol. 13, No. 5, 04.03.2011, p. 1258-1260.

Research output: Contribution to journalArticle

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