Abstract

The location and function of iron in the central nervous system are reviewed with particular emphasis on human biology. Iron is distributed to different cell types in the brain in a heterogeneous fashion through the action of transferrin, transferrin receptors, and the metabolic needs of those cells. The function of this iron and its storage is documented in states of growth and development as well as during pathological states associated with aging. The information relating this biology to current observations of attention deficits in iron‐deficient humans is also reviewed.

Original languageEnglish (US)
Pages (from-to)157-170
Number of pages14
JournalNutrition reviews
Volume51
Issue number6
DOIs
StatePublished - Jan 1 1993

Fingerprint

Iron
Brain
Transferrin Receptors
Transferrin
Growth and Development
Central Nervous System

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

Cite this

Beard, John L. ; Connor, James ; Jones, Byron C. / Iron in the Brain. In: Nutrition reviews. 1993 ; Vol. 51, No. 6. pp. 157-170.
@article{534efa48343043638c6a36624ba25339,
title = "Iron in the Brain",
abstract = "The location and function of iron in the central nervous system are reviewed with particular emphasis on human biology. Iron is distributed to different cell types in the brain in a heterogeneous fashion through the action of transferrin, transferrin receptors, and the metabolic needs of those cells. The function of this iron and its storage is documented in states of growth and development as well as during pathological states associated with aging. The information relating this biology to current observations of attention deficits in iron‐deficient humans is also reviewed.",
author = "Beard, {John L.} and James Connor and Jones, {Byron C.}",
year = "1993",
month = "1",
day = "1",
doi = "10.1111/j.1753-4887.1993.tb03096.x",
language = "English (US)",
volume = "51",
pages = "157--170",
journal = "Nutrition Reviews",
issn = "0029-6643",
publisher = "Wiley-Blackwell",
number = "6",

}

Iron in the Brain. / Beard, John L.; Connor, James; Jones, Byron C.

In: Nutrition reviews, Vol. 51, No. 6, 01.01.1993, p. 157-170.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Iron in the Brain

AU - Beard, John L.

AU - Connor, James

AU - Jones, Byron C.

PY - 1993/1/1

Y1 - 1993/1/1

N2 - The location and function of iron in the central nervous system are reviewed with particular emphasis on human biology. Iron is distributed to different cell types in the brain in a heterogeneous fashion through the action of transferrin, transferrin receptors, and the metabolic needs of those cells. The function of this iron and its storage is documented in states of growth and development as well as during pathological states associated with aging. The information relating this biology to current observations of attention deficits in iron‐deficient humans is also reviewed.

AB - The location and function of iron in the central nervous system are reviewed with particular emphasis on human biology. Iron is distributed to different cell types in the brain in a heterogeneous fashion through the action of transferrin, transferrin receptors, and the metabolic needs of those cells. The function of this iron and its storage is documented in states of growth and development as well as during pathological states associated with aging. The information relating this biology to current observations of attention deficits in iron‐deficient humans is also reviewed.

UR - http://www.scopus.com/inward/record.url?scp=0027220147&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027220147&partnerID=8YFLogxK

U2 - 10.1111/j.1753-4887.1993.tb03096.x

DO - 10.1111/j.1753-4887.1993.tb03096.x

M3 - Review article

C2 - 8371846

AN - SCOPUS:0027220147

VL - 51

SP - 157

EP - 170

JO - Nutrition Reviews

JF - Nutrition Reviews

SN - 0029-6643

IS - 6

ER -