Is there an association between hyperglycemia and clinical outcome in adult patients receiving extracorporeal membrane oxygenation

Song Lou, Jingwen Li, Cun Long, Feilong Hei, Kun Yu, Shigang Wang

Research output: Contribution to journalArticle

Abstract

Perioperative hyperglycemia frequently develops in critically ill patients and has been associated with adverse outcome. In this study, we tried to identify whether hyperglycemia was associated with adverse outcome in adult patients receiving extracorporeal membrane oxygenation. From 2004 through 2008, 44 adult patients received extracorporeal membrane oxygenation. Clinical records of these 44 consecutive patients were retrospectively analyzed. Glucose levels were monitored and recorded every 3 hours during the support period. The mean glucose level was computed for all patients for whom data were available within the first 48 hours after extracorporeal membrane oxygenation setup. More than 15% of blood glucose levels above 180 mg/dL were defined as hyperglycemia. Clinical outcomes were compared between patients with and without hyperglycemia. The primary outcome was death from any cause in hospital. A p value < .05 was accepted as significant. The overall survival was 68%. Twenty-eight patients were allocated to group 1 with a mean glucose of 179 ± 40 mg per deciliter. The other 16 patients allocated to group 2 with a mean glucose of 140 ± 16 mg per deciliter. There is no significant difference in the mortality of the two groups. Perioperative complications were also similar between the two groups. Glucose levels were not associated with mortality and complications in adult patients receiving extracorporeal membrane oxygenation.

Original languageEnglish (US)
Pages (from-to)281-285
Number of pages5
JournalJournal of Extra-Corporeal Technology
Volume42
Issue number4
StatePublished - Dec 2010

Fingerprint

Extracorporeal Membrane Oxygenation
Hyperglycemia
Glucose
Mortality
Critical Illness
Blood Glucose
Cause of Death
Survival

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Cardiology and Cardiovascular Medicine
  • Health Professions (miscellaneous)

Cite this

Lou, Song ; Li, Jingwen ; Long, Cun ; Hei, Feilong ; Yu, Kun ; Wang, Shigang. / Is there an association between hyperglycemia and clinical outcome in adult patients receiving extracorporeal membrane oxygenation. In: Journal of Extra-Corporeal Technology. 2010 ; Vol. 42, No. 4. pp. 281-285.
@article{345d8ae702df404188fe694dd22eaf26,
title = "Is there an association between hyperglycemia and clinical outcome in adult patients receiving extracorporeal membrane oxygenation",
abstract = "Perioperative hyperglycemia frequently develops in critically ill patients and has been associated with adverse outcome. In this study, we tried to identify whether hyperglycemia was associated with adverse outcome in adult patients receiving extracorporeal membrane oxygenation. From 2004 through 2008, 44 adult patients received extracorporeal membrane oxygenation. Clinical records of these 44 consecutive patients were retrospectively analyzed. Glucose levels were monitored and recorded every 3 hours during the support period. The mean glucose level was computed for all patients for whom data were available within the first 48 hours after extracorporeal membrane oxygenation setup. More than 15{\%} of blood glucose levels above 180 mg/dL were defined as hyperglycemia. Clinical outcomes were compared between patients with and without hyperglycemia. The primary outcome was death from any cause in hospital. A p value < .05 was accepted as significant. The overall survival was 68{\%}. Twenty-eight patients were allocated to group 1 with a mean glucose of 179 ± 40 mg per deciliter. The other 16 patients allocated to group 2 with a mean glucose of 140 ± 16 mg per deciliter. There is no significant difference in the mortality of the two groups. Perioperative complications were also similar between the two groups. Glucose levels were not associated with mortality and complications in adult patients receiving extracorporeal membrane oxygenation.",
author = "Song Lou and Jingwen Li and Cun Long and Feilong Hei and Kun Yu and Shigang Wang",
year = "2010",
month = "12",
language = "English (US)",
volume = "42",
pages = "281--285",
journal = "Journal of Extra-Corporeal Technology",
issn = "0022-1058",
publisher = "American Society of Extra-Corporeal Technology",
number = "4",

}

Is there an association between hyperglycemia and clinical outcome in adult patients receiving extracorporeal membrane oxygenation. / Lou, Song; Li, Jingwen; Long, Cun; Hei, Feilong; Yu, Kun; Wang, Shigang.

In: Journal of Extra-Corporeal Technology, Vol. 42, No. 4, 12.2010, p. 281-285.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Is there an association between hyperglycemia and clinical outcome in adult patients receiving extracorporeal membrane oxygenation

AU - Lou, Song

AU - Li, Jingwen

AU - Long, Cun

AU - Hei, Feilong

AU - Yu, Kun

AU - Wang, Shigang

PY - 2010/12

Y1 - 2010/12

N2 - Perioperative hyperglycemia frequently develops in critically ill patients and has been associated with adverse outcome. In this study, we tried to identify whether hyperglycemia was associated with adverse outcome in adult patients receiving extracorporeal membrane oxygenation. From 2004 through 2008, 44 adult patients received extracorporeal membrane oxygenation. Clinical records of these 44 consecutive patients were retrospectively analyzed. Glucose levels were monitored and recorded every 3 hours during the support period. The mean glucose level was computed for all patients for whom data were available within the first 48 hours after extracorporeal membrane oxygenation setup. More than 15% of blood glucose levels above 180 mg/dL were defined as hyperglycemia. Clinical outcomes were compared between patients with and without hyperglycemia. The primary outcome was death from any cause in hospital. A p value < .05 was accepted as significant. The overall survival was 68%. Twenty-eight patients were allocated to group 1 with a mean glucose of 179 ± 40 mg per deciliter. The other 16 patients allocated to group 2 with a mean glucose of 140 ± 16 mg per deciliter. There is no significant difference in the mortality of the two groups. Perioperative complications were also similar between the two groups. Glucose levels were not associated with mortality and complications in adult patients receiving extracorporeal membrane oxygenation.

AB - Perioperative hyperglycemia frequently develops in critically ill patients and has been associated with adverse outcome. In this study, we tried to identify whether hyperglycemia was associated with adverse outcome in adult patients receiving extracorporeal membrane oxygenation. From 2004 through 2008, 44 adult patients received extracorporeal membrane oxygenation. Clinical records of these 44 consecutive patients were retrospectively analyzed. Glucose levels were monitored and recorded every 3 hours during the support period. The mean glucose level was computed for all patients for whom data were available within the first 48 hours after extracorporeal membrane oxygenation setup. More than 15% of blood glucose levels above 180 mg/dL were defined as hyperglycemia. Clinical outcomes were compared between patients with and without hyperglycemia. The primary outcome was death from any cause in hospital. A p value < .05 was accepted as significant. The overall survival was 68%. Twenty-eight patients were allocated to group 1 with a mean glucose of 179 ± 40 mg per deciliter. The other 16 patients allocated to group 2 with a mean glucose of 140 ± 16 mg per deciliter. There is no significant difference in the mortality of the two groups. Perioperative complications were also similar between the two groups. Glucose levels were not associated with mortality and complications in adult patients receiving extracorporeal membrane oxygenation.

UR - http://www.scopus.com/inward/record.url?scp=78751483261&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=78751483261&partnerID=8YFLogxK

M3 - Article

C2 - 21313925

AN - SCOPUS:78751483261

VL - 42

SP - 281

EP - 285

JO - Journal of Extra-Corporeal Technology

JF - Journal of Extra-Corporeal Technology

SN - 0022-1058

IS - 4

ER -