Ischemic stroke syndromes in childhood.

Research output: Contribution to journalReview article

42 Citations (Scopus)

Abstract

Cerebral ischemic injury is uncommon in children, but the effects are long-lasting with significant implications for the child's development. The precipitating event in ischemic infarct is generally occlusion of the cerebral vessels. This occlusion may the result of direct injury of the cerebral vasculature, thrombus formation, or emboli from more distant sources. A wide variety of conditions are known to predispose to cerebral infarcts in children. However, even in recent studies, the underlying condition is unknown in as many as half the children who suffer an ischemic stroke. To care for these children effectively, it is imperative that extensive evaluations be performed to determine the cause of the cerebral infarct. Furthermore, increasing attention will need to be directed toward the metabolic events of cerebral ischemia. A better understanding of these mechanisms may provide clues to some of the causes of ischemic injury and should lead to more effective treatments.

Original languageEnglish (US)
Pages (from-to)374-383
Number of pages10
JournalPediatric Annals
Volume21
Issue number6
DOIs
StatePublished - Jan 1 1992

Fingerprint

Stroke
Wounds and Injuries
Intracranial Thrombosis
Child Care
Child Development
Embolism
Brain Ischemia
Therapeutics

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health

Cite this

@article{c91a4b6bcf5d49f182c2b1b67ca6ee6a,
title = "Ischemic stroke syndromes in childhood.",
abstract = "Cerebral ischemic injury is uncommon in children, but the effects are long-lasting with significant implications for the child's development. The precipitating event in ischemic infarct is generally occlusion of the cerebral vessels. This occlusion may the result of direct injury of the cerebral vasculature, thrombus formation, or emboli from more distant sources. A wide variety of conditions are known to predispose to cerebral infarcts in children. However, even in recent studies, the underlying condition is unknown in as many as half the children who suffer an ischemic stroke. To care for these children effectively, it is imperative that extensive evaluations be performed to determine the cause of the cerebral infarct. Furthermore, increasing attention will need to be directed toward the metabolic events of cerebral ischemia. A better understanding of these mechanisms may provide clues to some of the causes of ischemic injury and should lead to more effective treatments.",
author = "William Trescher",
year = "1992",
month = "1",
day = "1",
doi = "10.3928/0090-4481-19920601-10",
language = "English (US)",
volume = "21",
pages = "374--383",
journal = "Pediatric Annals",
issn = "0090-4481",
publisher = "Slack Incorporated",
number = "6",

}

Ischemic stroke syndromes in childhood. / Trescher, William.

In: Pediatric Annals, Vol. 21, No. 6, 01.01.1992, p. 374-383.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Ischemic stroke syndromes in childhood.

AU - Trescher, William

PY - 1992/1/1

Y1 - 1992/1/1

N2 - Cerebral ischemic injury is uncommon in children, but the effects are long-lasting with significant implications for the child's development. The precipitating event in ischemic infarct is generally occlusion of the cerebral vessels. This occlusion may the result of direct injury of the cerebral vasculature, thrombus formation, or emboli from more distant sources. A wide variety of conditions are known to predispose to cerebral infarcts in children. However, even in recent studies, the underlying condition is unknown in as many as half the children who suffer an ischemic stroke. To care for these children effectively, it is imperative that extensive evaluations be performed to determine the cause of the cerebral infarct. Furthermore, increasing attention will need to be directed toward the metabolic events of cerebral ischemia. A better understanding of these mechanisms may provide clues to some of the causes of ischemic injury and should lead to more effective treatments.

AB - Cerebral ischemic injury is uncommon in children, but the effects are long-lasting with significant implications for the child's development. The precipitating event in ischemic infarct is generally occlusion of the cerebral vessels. This occlusion may the result of direct injury of the cerebral vasculature, thrombus formation, or emboli from more distant sources. A wide variety of conditions are known to predispose to cerebral infarcts in children. However, even in recent studies, the underlying condition is unknown in as many as half the children who suffer an ischemic stroke. To care for these children effectively, it is imperative that extensive evaluations be performed to determine the cause of the cerebral infarct. Furthermore, increasing attention will need to be directed toward the metabolic events of cerebral ischemia. A better understanding of these mechanisms may provide clues to some of the causes of ischemic injury and should lead to more effective treatments.

UR - http://www.scopus.com/inward/record.url?scp=0026870799&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026870799&partnerID=8YFLogxK

U2 - 10.3928/0090-4481-19920601-10

DO - 10.3928/0090-4481-19920601-10

M3 - Review article

C2 - 1620562

AN - SCOPUS:0026870799

VL - 21

SP - 374

EP - 383

JO - Pediatric Annals

JF - Pediatric Annals

SN - 0090-4481

IS - 6

ER -