Isolated sciatic neuropathy as an initial manifestation of a high grade B-cell lymphoma: A case report and literature review

Wenzhuan He, Weizhen Wang, Cristy Gustas, Jozef Malysz, Divpreet Kaur

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

Sciatic nerve neuropathy due to infiltrating of a high grade B-cell lymphoma is a very rare situation and has not often been reported. We report a case with a previous history of indolent lymphoma who presented with isolated sciatic nerve neuropathy and was found to have diffuse large B cell lymphoma involving the sciatic nerve. Although the current case is not a primary sciatic nerve lymphoma given the systematic involvement shown on MRI and PET/CT scan, the case represents a neurolymphomatosis of the sciatic nerve given the direct invasion of the lymphoma cells into the sciatic nerve. Due to the rarity of this condition, we subsequently reviewed related literatures.

Original languageEnglish (US)
Pages (from-to)147-153
Number of pages7
JournalClinical Neurology and Neurosurgery
Volume149
DOIs
StatePublished - Oct 1 2016

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Sciatic Neuropathy
B-Cell Lymphoma
Sciatic Nerve
Non-Hodgkin's Lymphoma
Lymphoma
Marek Disease
Lymphoma, Large B-Cell, Diffuse

All Science Journal Classification (ASJC) codes

  • Surgery
  • Clinical Neurology

Cite this

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abstract = "Sciatic nerve neuropathy due to infiltrating of a high grade B-cell lymphoma is a very rare situation and has not often been reported. We report a case with a previous history of indolent lymphoma who presented with isolated sciatic nerve neuropathy and was found to have diffuse large B cell lymphoma involving the sciatic nerve. Although the current case is not a primary sciatic nerve lymphoma given the systematic involvement shown on MRI and PET/CT scan, the case represents a neurolymphomatosis of the sciatic nerve given the direct invasion of the lymphoma cells into the sciatic nerve. Due to the rarity of this condition, we subsequently reviewed related literatures.",
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Isolated sciatic neuropathy as an initial manifestation of a high grade B-cell lymphoma : A case report and literature review. / He, Wenzhuan; Wang, Weizhen; Gustas, Cristy; Malysz, Jozef; Kaur, Divpreet.

In: Clinical Neurology and Neurosurgery, Vol. 149, 01.10.2016, p. 147-153.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Isolated sciatic neuropathy as an initial manifestation of a high grade B-cell lymphoma

T2 - A case report and literature review

AU - He, Wenzhuan

AU - Wang, Weizhen

AU - Gustas, Cristy

AU - Malysz, Jozef

AU - Kaur, Divpreet

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AB - Sciatic nerve neuropathy due to infiltrating of a high grade B-cell lymphoma is a very rare situation and has not often been reported. We report a case with a previous history of indolent lymphoma who presented with isolated sciatic nerve neuropathy and was found to have diffuse large B cell lymphoma involving the sciatic nerve. Although the current case is not a primary sciatic nerve lymphoma given the systematic involvement shown on MRI and PET/CT scan, the case represents a neurolymphomatosis of the sciatic nerve given the direct invasion of the lymphoma cells into the sciatic nerve. Due to the rarity of this condition, we subsequently reviewed related literatures.

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