Isolated undersized mitral annuloplasty for functional mitral regurgitation in non-ischemic dilated cardiomyopathy - Reconsideration of the relationship between preoperative coaptation depth and persistent mitral regurgitation

Takashi Miura, Kiyoyuki Eishi, Shiro Yamachika, Koji Hashizume, Seiichi Tada, Kentaro Yamane, Kazuyoshi Tanigawa, Shun Nakaji

Research output: Contribution to journalArticle

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Abstract

Background: A preoperative coaptation depth (CD) ≥11 mm is apparently a predictive factor for persistent mitral regurgitation (MR) after undersized mitral annuloplasty for functional MR. The results of studies of isolated undersized mitral annuloplasty in non-ischemic dilated cardiomyopathy (DCM) are reported, including the relationship between the preoperative CD and recurrent MR. Methods and Results: Six patients (mean age, 61 years) with severe functional MR in non-ischemic DCM underwent isolated undersized mitral annuloplasty. There were no hospital deaths. At intermediate follow-up of 2.2±1.9 years, New York Heart Association functional class improved significantly from 3.3±0.5 before surgery to 2.2±0.4 after surgery (p=0.0016). At a mean echocardiographic follow-up of 1.9±1.7 years, MR grade improved significantly from 4.0±0.0 before surgery to 1.0±0.6 after surgery (p<0.001). In 4 of 5 patients with a preoperative CD ≥11 mm, functional MR improved to mild or less than mild after surgery. Conclusions: Isolated undersized mitral annuloplasty improved clinical symptoms and functional MR in nonischemic DCM. These results suggest that preoperative CD ≥11 mm does not always predict recurrent MR after isolated undersized mitral annuloplasty for functional MR in cases of non-ischemic DCM.

Original languageEnglish (US)
Pages (from-to)1744-1750
Number of pages7
JournalCirculation Journal
Volume72
Issue number11
DOIs
StatePublished - Nov 12 2008

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Mitral Valve Annuloplasty
Dilated Cardiomyopathy
Mitral Valve Insufficiency

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

@article{8ace71304a974ee2a5622e0210ecfc79,
title = "Isolated undersized mitral annuloplasty for functional mitral regurgitation in non-ischemic dilated cardiomyopathy - Reconsideration of the relationship between preoperative coaptation depth and persistent mitral regurgitation",
abstract = "Background: A preoperative coaptation depth (CD) ≥11 mm is apparently a predictive factor for persistent mitral regurgitation (MR) after undersized mitral annuloplasty for functional MR. The results of studies of isolated undersized mitral annuloplasty in non-ischemic dilated cardiomyopathy (DCM) are reported, including the relationship between the preoperative CD and recurrent MR. Methods and Results: Six patients (mean age, 61 years) with severe functional MR in non-ischemic DCM underwent isolated undersized mitral annuloplasty. There were no hospital deaths. At intermediate follow-up of 2.2±1.9 years, New York Heart Association functional class improved significantly from 3.3±0.5 before surgery to 2.2±0.4 after surgery (p=0.0016). At a mean echocardiographic follow-up of 1.9±1.7 years, MR grade improved significantly from 4.0±0.0 before surgery to 1.0±0.6 after surgery (p<0.001). In 4 of 5 patients with a preoperative CD ≥11 mm, functional MR improved to mild or less than mild after surgery. Conclusions: Isolated undersized mitral annuloplasty improved clinical symptoms and functional MR in nonischemic DCM. These results suggest that preoperative CD ≥11 mm does not always predict recurrent MR after isolated undersized mitral annuloplasty for functional MR in cases of non-ischemic DCM.",
author = "Takashi Miura and Kiyoyuki Eishi and Shiro Yamachika and Koji Hashizume and Seiichi Tada and Kentaro Yamane and Kazuyoshi Tanigawa and Shun Nakaji",
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Isolated undersized mitral annuloplasty for functional mitral regurgitation in non-ischemic dilated cardiomyopathy - Reconsideration of the relationship between preoperative coaptation depth and persistent mitral regurgitation. / Miura, Takashi; Eishi, Kiyoyuki; Yamachika, Shiro; Hashizume, Koji; Tada, Seiichi; Yamane, Kentaro; Tanigawa, Kazuyoshi; Nakaji, Shun.

In: Circulation Journal, Vol. 72, No. 11, 12.11.2008, p. 1744-1750.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Isolated undersized mitral annuloplasty for functional mitral regurgitation in non-ischemic dilated cardiomyopathy - Reconsideration of the relationship between preoperative coaptation depth and persistent mitral regurgitation

AU - Miura, Takashi

AU - Eishi, Kiyoyuki

AU - Yamachika, Shiro

AU - Hashizume, Koji

AU - Tada, Seiichi

AU - Yamane, Kentaro

AU - Tanigawa, Kazuyoshi

AU - Nakaji, Shun

PY - 2008/11/12

Y1 - 2008/11/12

N2 - Background: A preoperative coaptation depth (CD) ≥11 mm is apparently a predictive factor for persistent mitral regurgitation (MR) after undersized mitral annuloplasty for functional MR. The results of studies of isolated undersized mitral annuloplasty in non-ischemic dilated cardiomyopathy (DCM) are reported, including the relationship between the preoperative CD and recurrent MR. Methods and Results: Six patients (mean age, 61 years) with severe functional MR in non-ischemic DCM underwent isolated undersized mitral annuloplasty. There were no hospital deaths. At intermediate follow-up of 2.2±1.9 years, New York Heart Association functional class improved significantly from 3.3±0.5 before surgery to 2.2±0.4 after surgery (p=0.0016). At a mean echocardiographic follow-up of 1.9±1.7 years, MR grade improved significantly from 4.0±0.0 before surgery to 1.0±0.6 after surgery (p<0.001). In 4 of 5 patients with a preoperative CD ≥11 mm, functional MR improved to mild or less than mild after surgery. Conclusions: Isolated undersized mitral annuloplasty improved clinical symptoms and functional MR in nonischemic DCM. These results suggest that preoperative CD ≥11 mm does not always predict recurrent MR after isolated undersized mitral annuloplasty for functional MR in cases of non-ischemic DCM.

AB - Background: A preoperative coaptation depth (CD) ≥11 mm is apparently a predictive factor for persistent mitral regurgitation (MR) after undersized mitral annuloplasty for functional MR. The results of studies of isolated undersized mitral annuloplasty in non-ischemic dilated cardiomyopathy (DCM) are reported, including the relationship between the preoperative CD and recurrent MR. Methods and Results: Six patients (mean age, 61 years) with severe functional MR in non-ischemic DCM underwent isolated undersized mitral annuloplasty. There were no hospital deaths. At intermediate follow-up of 2.2±1.9 years, New York Heart Association functional class improved significantly from 3.3±0.5 before surgery to 2.2±0.4 after surgery (p=0.0016). At a mean echocardiographic follow-up of 1.9±1.7 years, MR grade improved significantly from 4.0±0.0 before surgery to 1.0±0.6 after surgery (p<0.001). In 4 of 5 patients with a preoperative CD ≥11 mm, functional MR improved to mild or less than mild after surgery. Conclusions: Isolated undersized mitral annuloplasty improved clinical symptoms and functional MR in nonischemic DCM. These results suggest that preoperative CD ≥11 mm does not always predict recurrent MR after isolated undersized mitral annuloplasty for functional MR in cases of non-ischemic DCM.

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U2 - 10.1253/circj.CJ-07-0983

DO - 10.1253/circj.CJ-07-0983

M3 - Article

VL - 72

SP - 1744

EP - 1750

JO - Circulation Journal

JF - Circulation Journal

SN - 1346-9843

IS - 11

ER -