Isolation and N-terminal amino acid sequence of membrane-bound human HLA-A and HLA-B antigens

John Bridgen, David Snary, Michael J. Crumpton, Colin Barnstable, Peter Goodfellow, Walter F. Bodmer

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Abstract

Membrane-bound HLA-A and HLA-B antigens have been extensively purified in good yield. The sequences of the N-terminal 16 amino acids have been determined using about 1 nmol of protein eluted from polyacrylamide gel after electrophoresis in sodium dodecyl sulphate.

Original languageEnglish (US)
Pages (from-to)200-205
Number of pages6
JournalNature
Volume261
Issue number5557
DOIs
StatePublished - Dec 1 1976

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Cite this

Bridgen, J., Snary, D., Crumpton, M. J., Barnstable, C., Goodfellow, P., & Bodmer, W. F. (1976). Isolation and N-terminal amino acid sequence of membrane-bound human HLA-A and HLA-B antigens. Nature, 261(5557), 200-205. https://doi.org/10.1038/261200a0