JC virus small t antigen binds phosphatase PP2A and Rb family proteins and is required for efficient viral DNA replication activity

Medicine & Life Sciences

• JC Virus 80%
• Protein Phosphatase 2 74%
• Retinoblastoma Protein 72%
• Viral DNA 64%
• Neoplasm Antigens 60%
• Phosphoric Monoester Hydrolases 58%
• DNA Replication 57%
• Antigens 36%
• Polyomavirus 8%
• Proteins 8%
• Tumor Suppressor Proteins 4%
• Conserved Sequence 4%
• RNA Precursors 3%
• Mutant Proteins 3%
• Proline 3%
• Neoplasms 3%
• Primates 3%
• Cell Cycle 2%
• Cell Survival 2%
• Genome 2%
• Cell Proliferation 2%

Agriculture & Biology

• Human polyomavirus 2 100%
• phosphoprotein phosphatase 74%
• DNA replication 60%
• neoplasms 43%
• antigens 42%
• proteins 19%
• Polyomaviridae 8%
• mutants 8%
• tumor suppressor proteins 4%
• alternative splicing 3%
• messenger RNA 2%
• cell viability 2%
• cell proliferation 2%
• cell cycle 2%
• Primates 2%
• proline 2%
• genome 1%
• DNA 1%
• cells 0%
• methodology 0%

Chemical Compounds

• Antigen 47%
• Protein 23%
• Tumor Suppressor Protein 5%
• Messenger RNA 4%
• Proline 3%
• Substitution Reaction 2%