Keratins Are Going Nuclear

Ryan P. Hobbs, Justin T. Jacob, Pierre A. Coulombe

Research output: Contribution to journalComment/debate

21 Scopus citations

Abstract

Previously thought to reside exclusively in the cytoplasm, the cytoskeletal protein keratin 17 (K17) has been recently identified inside the nucleus of tumor epithelial cells with a direct impact on cell proliferation and gene expression. We comment on fundamental questions raised by this new finding and the associated significance.

Original languageEnglish (US)
Pages (from-to)227-233
Number of pages7
JournalDevelopmental Cell
Volume38
Issue number3
DOIs
StatePublished - Aug 8 2016

All Science Journal Classification (ASJC) codes

  • Molecular Biology
  • Biochemistry, Genetics and Molecular Biology(all)
  • Developmental Biology
  • Cell Biology

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