Keratoacanthoma-Like Growths of Incontinentia Pigmenti Successfully Treated with Intralesional Methotrexate

Brittany Barros, Klaus Helm, Andrea Zaenglein, Elizabeth Seiverling

Research output: Contribution to journalArticle

Abstract

We report the case of a 17-year-old girl with incontinentia pigmenti who developed multiple large hyperkeratotic tumors within Blaschkoid hyperpigmented patches on her left leg. Biopsy demonstrated an endoexophytic nodule with irregular invaginations of keratinizing squamous epithelium and a central keratin-filled crater, consistent with keratoacanthoma-like lesions of incontinentia pigmenti. The tumors were successfully treated with intralesional methotrexate.

Original languageEnglish (US)
Pages (from-to)e203-e204
JournalPediatric Dermatology
Volume34
Issue number4
DOIs
StatePublished - Jul 1 2017

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Incontinentia Pigmenti
Keratoacanthoma
Methotrexate
Growth
Keratins
Neoplasms
Leg
Epithelium
Biopsy

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Dermatology

Cite this

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abstract = "We report the case of a 17-year-old girl with incontinentia pigmenti who developed multiple large hyperkeratotic tumors within Blaschkoid hyperpigmented patches on her left leg. Biopsy demonstrated an endoexophytic nodule with irregular invaginations of keratinizing squamous epithelium and a central keratin-filled crater, consistent with keratoacanthoma-like lesions of incontinentia pigmenti. The tumors were successfully treated with intralesional methotrexate.",
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Keratoacanthoma-Like Growths of Incontinentia Pigmenti Successfully Treated with Intralesional Methotrexate. / Barros, Brittany; Helm, Klaus; Zaenglein, Andrea; Seiverling, Elizabeth.

In: Pediatric Dermatology, Vol. 34, No. 4, 01.07.2017, p. e203-e204.

Research output: Contribution to journalArticle

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