LATE MERISTEM IDENTITY2 acts together with LEAFY to activate APETALA1

Jennifer J. Pastore, Andrea Limpuangthip, Nobutoshi Yamaguchi, Miin Feng Wu, Yi Sang, Soon Ki Han, Lauren Malaspina, Natasha Chavdaroff, Ayako Yamaguchi, Doris Wagner

Research output: Contribution to journalArticle

49 Citations (Scopus)

Abstract

The switch from producing vegetative structures (branches and leaves) to producing reproductive structures (flowers) is a crucial developmental transition that significantly affects the reproductive success of flowering plants. In Arabidopsis, this transition is in large part controlled by the meristem identity regulator LEAFY (LFY). The molecular mechanisms by which LFY orchestrates a precise and robust switch to flower formation is not well understood. Here, we show that the direct LFY target LATE MERISTEM IDENTITY2 (LMI2) has a role in the meristem identity transition. Like LFY, LMI2 activates AP1 directly; moreover, LMI2 and LFY interact physically. LFY, LMI2 and AP1 are connected in a feed-forward and positive feedback loop network. We propose that these intricate regulatory interactions not only direct the precision of this crucial developmental transition in rapidly changing environmental conditions, but also contribute to its robustness and irreversibility.

Original languageEnglish (US)
Pages (from-to)3189-3198
Number of pages10
JournalDevelopment
Volume138
Issue number15
DOIs
StatePublished - Aug 1 2011

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Meristem
Arabidopsis

All Science Journal Classification (ASJC) codes

  • Molecular Biology
  • Developmental Biology

Cite this

Pastore, J. J., Limpuangthip, A., Yamaguchi, N., Wu, M. F., Sang, Y., Han, S. K., ... Wagner, D. (2011). LATE MERISTEM IDENTITY2 acts together with LEAFY to activate APETALA1. Development, 138(15), 3189-3198. https://doi.org/10.1242/dev.063073
Pastore, Jennifer J. ; Limpuangthip, Andrea ; Yamaguchi, Nobutoshi ; Wu, Miin Feng ; Sang, Yi ; Han, Soon Ki ; Malaspina, Lauren ; Chavdaroff, Natasha ; Yamaguchi, Ayako ; Wagner, Doris. / LATE MERISTEM IDENTITY2 acts together with LEAFY to activate APETALA1. In: Development. 2011 ; Vol. 138, No. 15. pp. 3189-3198.
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Pastore, JJ, Limpuangthip, A, Yamaguchi, N, Wu, MF, Sang, Y, Han, SK, Malaspina, L, Chavdaroff, N, Yamaguchi, A & Wagner, D 2011, 'LATE MERISTEM IDENTITY2 acts together with LEAFY to activate APETALA1', Development, vol. 138, no. 15, pp. 3189-3198. https://doi.org/10.1242/dev.063073

LATE MERISTEM IDENTITY2 acts together with LEAFY to activate APETALA1. / Pastore, Jennifer J.; Limpuangthip, Andrea; Yamaguchi, Nobutoshi; Wu, Miin Feng; Sang, Yi; Han, Soon Ki; Malaspina, Lauren; Chavdaroff, Natasha; Yamaguchi, Ayako; Wagner, Doris.

In: Development, Vol. 138, No. 15, 01.08.2011, p. 3189-3198.

Research output: Contribution to journalArticle

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Pastore JJ, Limpuangthip A, Yamaguchi N, Wu MF, Sang Y, Han SK et al. LATE MERISTEM IDENTITY2 acts together with LEAFY to activate APETALA1. Development. 2011 Aug 1;138(15):3189-3198. https://doi.org/10.1242/dev.063073