Left atrial appendage occlusion: A critical appraisal updated with recent evidence

John M. Mandrola, Andrew J. Foy

Research output: Contribution to journalReview article

Abstract

Purpose of reviewTo allow readers to fully appreciate the uncertainties with this novel yet invasive approach to stroke prevention.Recent findingsPercutaneous left atrial (LA) appendage occlusion has emerged as potential nonpharmacologic means to prevent stroke and systemic embolism in patients with atrial fibrillation. Yet the evidence underpinning this new technology is not definitive.SummaryIn this review, we consider the internal and external validity of the regulatory trials, pathophysiologic basis for LA appendage occlusion and clinical tradeoffs of the procedure.

Original languageEnglish (US)
Pages (from-to)30-34
Number of pages5
JournalCurrent Opinion in Cardiology
Volume35
Issue number1
DOIs
StatePublished - Jan 1 2020

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

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