Levodopa therapy improves motor function in HIV-infected children with extrapyramidal syndromes

M. Mintz, M. Tardieu, L. Hoyt, G. McSherry, J. Mendelson, J. Oleske

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Five children with human immunodeficiency virus type-1 (HIV-1) infection, aged 4 to 13 years, manifested extrapyramidal dysfunction characterized by rigidity/stiffness, ambulation difficulties/shuffling gait, dysarthria/drooling/swallowing dysfunction, hypomimetic/inexpressive facies, and bradykinesia. Levodopa therapy caused an initial improvement in all symptoms, and the effect was sustained in most patients. Levodopa is a useful adjunctive therapy in HIV-1 infected children with extrapyramidal syndromes, by enhancing motor function and improving their quality of life.

Original languageEnglish (US)
Pages (from-to)1583-1585
Number of pages3
Issue number6
Publication statusPublished - Dec 1996


All Science Journal Classification (ASJC) codes

  • Clinical Neurology

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