Lipid Feeding and Milk Fat Depression

Thomas C. Jenkins, Kevin John Harvatine

Research output: Contribution to journalReview article

23 Citations (Scopus)

Abstract

Diets fed to cattle contain mostly unsaturated fatty acids supplied in grains and forages, by-products, and fat supplements. Lipid intake by dairy cattle must be restricted to prevent alterations of microbial populations in the rumen that can negatively affect milk yield. Unsaturated fatty acids consumed by cattle are extensively metabolized through biohydrogenation, intermediates of which include conjugated linoleic acid (CLA) and trans-monoenoic acid isomers. Three specific CLA intermediates of biohydrogenation have been shown to cause milk fat depression in dairy cattle through coordinated suppression of mammary lipogenic genes by a transcription factor that is a central regulator of lipid synthesis.

Original languageEnglish (US)
Pages (from-to)623-642
Number of pages20
JournalVeterinary Clinics of North America - Food Animal Practice
Volume30
Issue number3
DOIs
StatePublished - Jan 1 2014

Fingerprint

biohydrogenation
conjugated linoleic acid
unsaturated fatty acids
milk fat
dairy cattle
Milk
Fats
Lipids
Conjugated Linoleic Acids
cattle
fat intake
lipids
Unsaturated Fatty Acids
byproducts
breasts
isomers
milk yield
rumen
transcription factors
forage

All Science Journal Classification (ASJC) codes

  • Food Animals

Cite this

@article{8968105942324a21a143d390a1184854,
title = "Lipid Feeding and Milk Fat Depression",
abstract = "Diets fed to cattle contain mostly unsaturated fatty acids supplied in grains and forages, by-products, and fat supplements. Lipid intake by dairy cattle must be restricted to prevent alterations of microbial populations in the rumen that can negatively affect milk yield. Unsaturated fatty acids consumed by cattle are extensively metabolized through biohydrogenation, intermediates of which include conjugated linoleic acid (CLA) and trans-monoenoic acid isomers. Three specific CLA intermediates of biohydrogenation have been shown to cause milk fat depression in dairy cattle through coordinated suppression of mammary lipogenic genes by a transcription factor that is a central regulator of lipid synthesis.",
author = "Jenkins, {Thomas C.} and Harvatine, {Kevin John}",
year = "2014",
month = "1",
day = "1",
doi = "10.1016/j.cvfa.2014.07.006",
language = "English (US)",
volume = "30",
pages = "623--642",
journal = "Veterinary Clinics of North America - Food Animal Practice",
issn = "0749-0720",
publisher = "W.B. Saunders Ltd",
number = "3",

}

Lipid Feeding and Milk Fat Depression. / Jenkins, Thomas C.; Harvatine, Kevin John.

In: Veterinary Clinics of North America - Food Animal Practice, Vol. 30, No. 3, 01.01.2014, p. 623-642.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Lipid Feeding and Milk Fat Depression

AU - Jenkins, Thomas C.

AU - Harvatine, Kevin John

PY - 2014/1/1

Y1 - 2014/1/1

N2 - Diets fed to cattle contain mostly unsaturated fatty acids supplied in grains and forages, by-products, and fat supplements. Lipid intake by dairy cattle must be restricted to prevent alterations of microbial populations in the rumen that can negatively affect milk yield. Unsaturated fatty acids consumed by cattle are extensively metabolized through biohydrogenation, intermediates of which include conjugated linoleic acid (CLA) and trans-monoenoic acid isomers. Three specific CLA intermediates of biohydrogenation have been shown to cause milk fat depression in dairy cattle through coordinated suppression of mammary lipogenic genes by a transcription factor that is a central regulator of lipid synthesis.

AB - Diets fed to cattle contain mostly unsaturated fatty acids supplied in grains and forages, by-products, and fat supplements. Lipid intake by dairy cattle must be restricted to prevent alterations of microbial populations in the rumen that can negatively affect milk yield. Unsaturated fatty acids consumed by cattle are extensively metabolized through biohydrogenation, intermediates of which include conjugated linoleic acid (CLA) and trans-monoenoic acid isomers. Three specific CLA intermediates of biohydrogenation have been shown to cause milk fat depression in dairy cattle through coordinated suppression of mammary lipogenic genes by a transcription factor that is a central regulator of lipid synthesis.

UR - http://www.scopus.com/inward/record.url?scp=84908247690&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84908247690&partnerID=8YFLogxK

U2 - 10.1016/j.cvfa.2014.07.006

DO - 10.1016/j.cvfa.2014.07.006

M3 - Review article

C2 - 25239061

AN - SCOPUS:84908247690

VL - 30

SP - 623

EP - 642

JO - Veterinary Clinics of North America - Food Animal Practice

JF - Veterinary Clinics of North America - Food Animal Practice

SN - 0749-0720

IS - 3

ER -