Live capture of circulating tumor cells from human blood by a splitable 3D parylene membrane filtration device

Bo Lu, Siyang Zheng, Shuang Xie, Yu Chong Tai

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

In this work, a novel splitable 3D parylene membrane filter was designed, fabricated and tested. Viable tumor cells can be captured and kept alive for at least 20 days. Due to the "gap trapping mechanism" and splitable feature, we can release and collect trapped tumor cells from device after filtration. Combination of high capture efficiency, high throughput, low cost and viable capture makes it a promising candidate for detection and further study of circulating tumor cells.

Original languageEnglish (US)
Title of host publicationProceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society
Pages588-590
Number of pages3
ISBN (Print)9780979806421
StatePublished - Jan 1 2009
Event13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009 - Jeju, Korea, Republic of
Duration: Nov 1 2009Nov 5 2009

Publication series

NameProceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Other

Other13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009
CountryKorea, Republic of
CityJeju
Period11/1/0911/5/09

Fingerprint

Tumors
Blood
Cells
Membranes
Throughput
parylene
Costs

All Science Journal Classification (ASJC) codes

  • Chemical Engineering (miscellaneous)
  • Bioengineering

Cite this

Lu, B., Zheng, S., Xie, S., & Tai, Y. C. (2009). Live capture of circulating tumor cells from human blood by a splitable 3D parylene membrane filtration device. In Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 588-590). (Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences). Chemical and Biological Microsystems Society.
Lu, Bo ; Zheng, Siyang ; Xie, Shuang ; Tai, Yu Chong. / Live capture of circulating tumor cells from human blood by a splitable 3D parylene membrane filtration device. Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, 2009. pp. 588-590 (Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences).
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Lu, B, Zheng, S, Xie, S & Tai, YC 2009, Live capture of circulating tumor cells from human blood by a splitable 3D parylene membrane filtration device. in Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Chemical and Biological Microsystems Society, pp. 588-590, 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009, Jeju, Korea, Republic of, 11/1/09.

Live capture of circulating tumor cells from human blood by a splitable 3D parylene membrane filtration device. / Lu, Bo; Zheng, Siyang; Xie, Shuang; Tai, Yu Chong.

Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, 2009. p. 588-590 (Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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Lu B, Zheng S, Xie S, Tai YC. Live capture of circulating tumor cells from human blood by a splitable 3D parylene membrane filtration device. In Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society. 2009. p. 588-590. (Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences).