Liver diseases of pregnancy particular to the third trimester

Deidre T. Fisher, John Repke

Research output: Contribution to journalArticle

Abstract

Liver disease is a complication of pregnancy that, when it occurs, demands that one be vigilant in seeking the diagnosis for rapid and definitive treatment for the optimal outcome of both mother and fetus. Patients who present with liver abnormalities in the third trimester of pregnancy should be carefully evaluated. The differential diagnosis includes diseases that present specifically in the second or third trimester, such as acute fatty liver of pregnancy, preeclampsia or its Hemolysis, Elevated Liver function tests, Low Platelets (HELLP) syndrome variant, and intrahepatic cholestasis of pregnancy; diseases that can present at any gestational age, such as viral hepatitis, drug-induced hepatotoxicity, and cholestatic disease; and rare or uncommon diseases, such as Budd Chiari syndrome, autoimmune hepatitis, and the thrombotic microangiopathiopathies, namely, hemolytic-uremic syndrome or thrombotic thrombocytopenia purpura. Anyone presenting with a vague constellation of symptoms in latter pregnancy should be investigated further for symptoms or signs of serious liver disease.

Original languageEnglish (US)
Pages (from-to)36-42
Number of pages7
JournalPrimary Care Update for Ob/Gyns
Volume5
Issue number1
DOIs
StatePublished - Jan 1 1998

Fingerprint

Third Pregnancy Trimester
Liver Diseases
Pregnancy
Budd-Chiari Syndrome
Chemical and Drug Induced Liver Injury
Autoimmune Hepatitis
Hemolytic-Uremic Syndrome
Purpura
Pregnancy Complications
Liver Function Tests
Second Pregnancy Trimester
Hemolysis
Pre-Eclampsia
Thrombocytopenia
Gestational Age
Signs and Symptoms
Fetus
Differential Diagnosis
Blood Platelets
Mothers

All Science Journal Classification (ASJC) codes

  • Nursing(all)
  • Obstetrics and Gynecology

Cite this

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Liver diseases of pregnancy particular to the third trimester. / Fisher, Deidre T.; Repke, John.

In: Primary Care Update for Ob/Gyns, Vol. 5, No. 1, 01.01.1998, p. 36-42.

Research output: Contribution to journalArticle

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