@article{fe73924317aa4629988a31e0fbb23311,
title = "Localization of a human Na+, K+-ATPase α subunit gene to chromosome 19q12{\aa}q13.2 and linkage to the myotonic dystrophy locus",
abstract = "The gene coding for a Na+,K+-ATPase α subunit (ATP1A3) has been localized to the q12{\aa}q13.2 region of human chromosome 19, potentially close to the myotonic dystrophy (DM) gene. In view of previous studies implicating a Na+,K+-ATPase in the pathology of DM, we have examined the possibility that ATP1A3 is a candidate for the DM locus. Although linked, several clear instances of recombination between ATP1A3 and DM rule out the possibility that mutations in ATP1A3 cause the disease. Examination of multiply informative pedigrees indicates the gene order DM-APOC2-ATP1A3.",
author = "Harley, {Helen G.} and {David Brook}, J. and Jackson, {Cynthia L.} and Thomas Glaser and Walsh, {Kathryn V.} and Mansoor Sarfarazi and Rachel Kent and Marie Lager and Manuela Koch and Harper, {Peter S.} and Robert Levenson and Housman, {David E.} and Shaw, {Duncan J.}",
note = "Funding Information: We thank Drs. F. E. Baralle and S. E. Humphries for APOC2 probes, Dr. E. A. Shephard for the CYPPA probe, and Drs. S. M. Huson and P. Lunt for help with family sampling. This work was supported by the Wolfson Foundation (UK), the Muscular Dystrophy Group of Great Britain, the Medical Research Council (UK), and Grant C4-26712 to the MIT Center for Cancer Research from the National Cancer Institute (R. Hynes, Principal Investigator). C.L.J. was supported by Public Health Service Grant GM10440 from the National Institute of General Medical Science and a fellowship awarded by the Charles A. King Trust Foundation.",
year = "1988",
month = nov,
doi = "10.1016/0888-7543(88)90131-0",
language = "English (US)",
volume = "3",
pages = "380--384",
journal = "Genomics",
issn = "0888-7543",
publisher = "Academic Press Inc.",
number = "4",
}