TY - JOUR
T1 - Long-term exposure to ambient air pollution (including PM 1 ) and metabolic syndrome
T2 - The 33 Communities Chinese Health Study (33CCHS)
AU - Yang, Bo Yi
AU - Qian, Zhengmin (Min)
AU - Li, Shanshan
AU - Fan, Shujun
AU - Chen, Gongbo
AU - Syberg, Kevin M.
AU - Xian, Hong
AU - Wang, Si Quan
AU - Ma, Huimin
AU - Chen, Duo Hong
AU - Yang, Mo
AU - Liu, Kang Kang
AU - Zeng, Xiao Wen
AU - Hu, Li Wen
AU - Guo, Yuming
AU - Dong, Guang Hui
N1 - Funding Information:
This work was funded by the National Key Research and Development Program of China (No. 2016YFC0207000); the National Natural Science Foundation of China (No. 91543208; No. 81703179); the National Natural Science Foundation of China (No.81673128); the Fundamental Research Funds for the Central Universities (No. 16ykzd02, 17ykpy16); and the Guangdong Province Natural Science Foundation (No. 2014A050503027; No. 2016A030313342). YG was supported by the Career Development Fellowship of Australian National Health and Medical Research Council (No. APP1107107). SL was supported by the Early Career Fellowship of Australian National Health and Medical Research Council (No. APP1109193).
PY - 2018/7
Y1 - 2018/7
N2 - Little evidence exists about the effects of long-term exposure to ambient air pollution on metabolic syndrome (MetS). This study aimed to determine the association between long-term ambient air pollution and MetS in China. A total of 15,477 adults who participated in the 33 Communities Chinese Health Study (33CCHS) in 2009 were evaluated. MetS was defined based on the recommendation by the Joint Interim Societies. Exposure to air pollutants was assessed using data from monitoring stations and a spatial statistical model (including particles with diameters ≤ 1.0 µm (PM 1 ), ≤ 2.5 µm (PM 2.5 ), and ≤ 10 µm (PM 10 ), sulfur dioxide (SO 2 ), nitrogen dioxide (NO 2 ), and ozone (O 3 )). Two-level logistic regression analyses were utilized to assess the associations between air pollutants and MetS. The prevalence of MetS was 30.37%. The adjusted odds ratio of MetS per 10 µg/m 3 increase in PM 1 , PM 2.5 , PM 10 , SO 2 , NO 2 , and O 3 were 1.12 (95% CI = 1.00–1.24), 1.09 (95% CI = 1.00–1.18), 1.13 (95% CI = 1.08–1.19), 1.10 (95% CI = 1.02–1.18), 1.33 (95% CI = 1.12–1.57), and 1.10 (95% CI = 1.01–1.18), respectively. Stratified analyses indicated that the above associations were stronger in participants with the demographic variables of males, < 50 years of age, and higher income, as well as with the behavioral characteristics of smoking, drinking, and consuming sugar-sweetened soft drinks frequently. This study indicates that long-term exposure to ambient air pollutants may increase the risk of MetS, especially among males, the young to middle aged, those of low income, and those with unhealthy lifestyles.
AB - Little evidence exists about the effects of long-term exposure to ambient air pollution on metabolic syndrome (MetS). This study aimed to determine the association between long-term ambient air pollution and MetS in China. A total of 15,477 adults who participated in the 33 Communities Chinese Health Study (33CCHS) in 2009 were evaluated. MetS was defined based on the recommendation by the Joint Interim Societies. Exposure to air pollutants was assessed using data from monitoring stations and a spatial statistical model (including particles with diameters ≤ 1.0 µm (PM 1 ), ≤ 2.5 µm (PM 2.5 ), and ≤ 10 µm (PM 10 ), sulfur dioxide (SO 2 ), nitrogen dioxide (NO 2 ), and ozone (O 3 )). Two-level logistic regression analyses were utilized to assess the associations between air pollutants and MetS. The prevalence of MetS was 30.37%. The adjusted odds ratio of MetS per 10 µg/m 3 increase in PM 1 , PM 2.5 , PM 10 , SO 2 , NO 2 , and O 3 were 1.12 (95% CI = 1.00–1.24), 1.09 (95% CI = 1.00–1.18), 1.13 (95% CI = 1.08–1.19), 1.10 (95% CI = 1.02–1.18), 1.33 (95% CI = 1.12–1.57), and 1.10 (95% CI = 1.01–1.18), respectively. Stratified analyses indicated that the above associations were stronger in participants with the demographic variables of males, < 50 years of age, and higher income, as well as with the behavioral characteristics of smoking, drinking, and consuming sugar-sweetened soft drinks frequently. This study indicates that long-term exposure to ambient air pollutants may increase the risk of MetS, especially among males, the young to middle aged, those of low income, and those with unhealthy lifestyles.
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U2 - 10.1016/j.envres.2018.02.029
DO - 10.1016/j.envres.2018.02.029
M3 - Article
C2 - 29501830
AN - SCOPUS:85042939201
VL - 164
SP - 204
EP - 211
JO - Environmental Research
JF - Environmental Research
SN - 0013-9351
ER -