Long-term followup of proximal femoral allografts

Edward Fox, Mohammad Anwar Hau, Mark C. Gebhardt, Francis J. Hornicek, William W. Tomford, Henry J. Mankin

Research output: Contribution to journalArticle

80 Citations (Scopus)

Abstract

Between 1972 and 1999, the orthopaedic service at the authors' institution treated 137 patients with proximal femoral bone lesions by resection and reconstruction with frozen allografts from cadavers. The data were entered into a computer program allowing a comprehensive analysis. Thirty-eight patients had proximal femoral osteoarticular allografts, 69 had allograft-endoprosthesis composites, 22 had intercalary allografts, and eight had an allograft arthrodesis. There were 74 complications in 54 of the 137 patients with allografts, which included 26 allograft fractures (19%), 15 infections (11%), and 20 nonunions (15%). The overall success rate for the patients with these procedures was 103 of 137 (75%) at a mean followup of 7.9 years ± 5.6 years. If the eight patients with tumor recurrences (surgical failures rather than allograft failures) are not included, the success rate is 103 of 129 (80%). Eighty-three of these patients (55 %) without any allograft complications who have been treated and followed up for at least 2 years had a 92% success rate. It is concluded that although allograft reconstruction after resection of the proximal femur for patients with aggressive or malignant tumors has a high complication rate, approximately 80% of the patients have a successful outcome.

Original languageEnglish (US)
Pages (from-to)106-113
Number of pages8
JournalClinical Orthopaedics and Related Research
Issue number397
DOIs
StatePublished - Jan 1 2002

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Thigh
Allografts
Arthrodesis
Cadaver
Femur
Orthopedics
Neoplasms
Software
Bone and Bones
Recurrence

All Science Journal Classification (ASJC) codes

  • Surgery
  • Orthopedics and Sports Medicine

Cite this

Fox, E., Hau, M. A., Gebhardt, M. C., Hornicek, F. J., Tomford, W. W., & Mankin, H. J. (2002). Long-term followup of proximal femoral allografts. Clinical Orthopaedics and Related Research, (397), 106-113. https://doi.org/10.1097/00003086-200204000-00015
Fox, Edward ; Hau, Mohammad Anwar ; Gebhardt, Mark C. ; Hornicek, Francis J. ; Tomford, William W. ; Mankin, Henry J. / Long-term followup of proximal femoral allografts. In: Clinical Orthopaedics and Related Research. 2002 ; No. 397. pp. 106-113.
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Fox, E, Hau, MA, Gebhardt, MC, Hornicek, FJ, Tomford, WW & Mankin, HJ 2002, 'Long-term followup of proximal femoral allografts', Clinical Orthopaedics and Related Research, no. 397, pp. 106-113. https://doi.org/10.1097/00003086-200204000-00015

Long-term followup of proximal femoral allografts. / Fox, Edward; Hau, Mohammad Anwar; Gebhardt, Mark C.; Hornicek, Francis J.; Tomford, William W.; Mankin, Henry J.

In: Clinical Orthopaedics and Related Research, No. 397, 01.01.2002, p. 106-113.

Research output: Contribution to journalArticle

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