LSPR sensing of molecular biothiols based on noncoupled gold nanorods

Chong Li, Chuanliu Wu, Jinsheng Zheng, Jinping Lai, Chenlong Zhang, Yibing Zhao

Research output: Contribution to journalArticle

40 Citations (Scopus)

Abstract

Au NRs protected with mPEG-SH molecules (mPEG-Au NRs) were demonstrated to be a promising platform for LSPR-based sensing of molecular biothiols in aqueous solution. Surface mPEG-SH molecules endow Au NRs with great stability and biocompatibility and no nonspecific adsorption of biomacromolecules. The LSPR band of mPEG-Au NRs displays a stability and linear response in the spectral shift with respect to a change in their surrounding refractive index with a sensitivity of 252 nm/RIU. The loose structure of mPEG-SH around the Au NRs offers free sites, thereby allowing molecular biothiols to bind onto the surfaces of Au NRs. The LSPR response and the sensitivity of Au NRs to biothiols such as GSH, Cys, Hcy, TGA, GSSG, and BSA were then studied.

Original languageEnglish (US)
Pages (from-to)9130-9135
Number of pages6
JournalLangmuir
Volume26
Issue number11
DOIs
StatePublished - Jun 1 2010

Fingerprint

Nanorods
Gold
nanorods
gold
Molecules
Glutathione Disulfide
sensitivity
biocompatibility
Biocompatibility
molecules
Refractive index
platforms
refractivity
aqueous solutions
Adsorption
adsorption
shift

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Condensed Matter Physics
  • Surfaces and Interfaces
  • Spectroscopy
  • Electrochemistry

Cite this

Li, C., Wu, C., Zheng, J., Lai, J., Zhang, C., & Zhao, Y. (2010). LSPR sensing of molecular biothiols based on noncoupled gold nanorods. Langmuir, 26(11), 9130-9135. https://doi.org/10.1021/la101285r
Li, Chong ; Wu, Chuanliu ; Zheng, Jinsheng ; Lai, Jinping ; Zhang, Chenlong ; Zhao, Yibing. / LSPR sensing of molecular biothiols based on noncoupled gold nanorods. In: Langmuir. 2010 ; Vol. 26, No. 11. pp. 9130-9135.
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Li, C, Wu, C, Zheng, J, Lai, J, Zhang, C & Zhao, Y 2010, 'LSPR sensing of molecular biothiols based on noncoupled gold nanorods', Langmuir, vol. 26, no. 11, pp. 9130-9135. https://doi.org/10.1021/la101285r

LSPR sensing of molecular biothiols based on noncoupled gold nanorods. / Li, Chong; Wu, Chuanliu; Zheng, Jinsheng; Lai, Jinping; Zhang, Chenlong; Zhao, Yibing.

In: Langmuir, Vol. 26, No. 11, 01.06.2010, p. 9130-9135.

Research output: Contribution to journalArticle

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