Lung fluke (Paragonimus africanus) infects Nigerian red-capped mangabeys and causes respiratory disease

Sagan Friant, Kelsey Brown, Mason T. Saari, Nicholas H. Segel, Julia Slezak, Tony L. Goldberg

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Eggs of the lung fluke genus Paragonimus were detected in red-capped mangabeys (. Cercocebus torquatus) in Nigeria. We assess the role of these primates as potential sylvatic hosts and the clinical effects of the parasite on monkeys. DNA sequenced from eggs in feces were 100% identical in the ITS2 region to Paragonimus africanus sequences from humans in Cameroon. Paragonimus-positive monkeys coughed more than uninfected monkeys. Experimental de-worming led to reduction in parasite intensity and a corresponding reduction of coughing to baseline levels in infected monkeys. This report provides the first evidence of Paragonimus sp. in C. torquatus, of P. africanus in Nigerian wildlife, and the first molecular evidence of the parasite in African wildlife. Coughing, sometimes interpreted as a communication behavior in primates, can actually indicate infection with lung parasites. Observations of coughing in primates may, in turn, provide a useful mechanism for surveillance of Paragonimus spp, which are re-emerging human pathogens, in wildlife reservoirs.

Original languageEnglish (US)
Pages (from-to)329-332
Number of pages4
JournalInternational Journal for Parasitology: Parasites and Wildlife
Volume4
Issue number3
DOIs
StatePublished - Dec 1 2015

Fingerprint

Cercocebus
lung flukes
Paragonimus
Trematoda
respiratory tract diseases
Haplorhini
monkeys
Parasites
Lung
Primates
parasites
wildlife
Eggs
Cameroon
Nigeria
Feces
animal communication
feces
lungs
Communication

All Science Journal Classification (ASJC) codes

  • Parasitology
  • Animal Science and Zoology
  • Infectious Diseases

Cite this

Friant, Sagan ; Brown, Kelsey ; Saari, Mason T. ; Segel, Nicholas H. ; Slezak, Julia ; Goldberg, Tony L. / Lung fluke (Paragonimus africanus) infects Nigerian red-capped mangabeys and causes respiratory disease. In: International Journal for Parasitology: Parasites and Wildlife. 2015 ; Vol. 4, No. 3. pp. 329-332.
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Lung fluke (Paragonimus africanus) infects Nigerian red-capped mangabeys and causes respiratory disease. / Friant, Sagan; Brown, Kelsey; Saari, Mason T.; Segel, Nicholas H.; Slezak, Julia; Goldberg, Tony L.

In: International Journal for Parasitology: Parasites and Wildlife, Vol. 4, No. 3, 01.12.2015, p. 329-332.

Research output: Contribution to journalArticle

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