Macrophages: An elusive yet emerging therapeutic target of atherosclerosis

Medicine & Life Sciences

• Atherosclerosis 89%
• Macrophages 77%
• Foam Cells 51%
• 2,3-dihydro-5-hydroxy-2,2-dipentyl-4,6-di-tert-butylbenzofuran 30%
• succinobucol 27%
• Apoptosis 25%
• Class E Scavenger Receptors 22%
• Sterol O-Acyltransferase 20%
• Cholesterol 20%
• Therapeutics 18%
• Clinical Trials 18%
• Scavenger Receptors 17%
• Matrix Metalloproteinase 3 17%
• Cholesterol Esters 16%
• Peroxisome Proliferator-Activated Receptors 16%
• Matrix Metalloproteinase Inhibitors 16%
• Hydrolases 16%
• Toll-Like Receptor 4 15%
• Apolipoprotein A-I 15%
• Endoplasmic Reticulum Stress 15%
• Cell Adhesion Molecules 15%
• Mitogen-Activated Protein Kinases 13%
• Dyslipidemias 13%
• Matrix Metalloproteinases 13%
• Free Radicals 13%
• Endothelium 12%
• Rupture 11%
• Monocytes 11%
• Nitric Oxide 11%
• Protein Isoforms 11%
• Adenosine Triphosphate 10%
• Antioxidants 10%
• Phosphorylation 9%
• Lipids 9%
• Inflammation 8%
• Pharmaceutical Preparations 5%
• Proteins 5%

Chemical Compounds

• Foam 100%
• Cholesterol 99%
• Matrix Metalloproteinase Inhibitor 56%
• Arachidonate 51%
• Cholesteryl Ester 49%
• Acyl-CoA 47%
• Apolipoprotein 45%
• Low-Density Lipoprotein 43%
• Nitric Oxide 35%
• Protein 30%
• Free Radical 29%
• Pharmacological Metabolism 28%
• Antioxidant Agent 28%
• Pharmaceutical 27%
• Lipid 25%