Malformations of dorsal induction

Sangam Kanekar, Heather Kaneda, Alexis Shively

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Dorsal induction includes the formation and closure of neural tube, occurs during 3-5 weeks of gestation. Neurulation occurs in two phases, primary neurulation (formation of the neural plate and subsequently neural tube) and secondary neurulation (formation of distal cord and sacral and coccygeal segments). Failure of dorsal induction leads to anencephaly, exencephaly, cephaloceles, Chiari malformation and spinal dysraphism. In this article we discuss the relevant embryology, etiopathology and detail imaging appearances of these malformations.

Original languageEnglish (US)
Pages (from-to)189-199
Number of pages11
JournalSeminars in Ultrasound, CT and MRI
Issue number3
StatePublished - Jun 2011

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging


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