Management of colitis caused by irradiation

J. Stanley Smith, H. E. Milford

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Radiation therapy has assumed a role of primary importance in the management of gynecologic and other malignant growths. To be effective, the treatment dosage must be adequate. However, with higher dosages for curative radiation therapy, damage from the treatment may promote prolonged morbidity and even death. The effects of this treatment may be intensified by predisposing conditions within the patient, but the damage seems to be related to the insertion of radium. Prior to therapy, each patient must be individualized, and any predisposing factors should be kept in mind during treatment to recognize and treat these complications early. Once complications have arisen, the most conservative modality of dealing with the irradiated tissue is best, since these areas of intestinal injury do not heal. This requires early diversion or resection as conservative therapy, because fistulas and bleeding will become recurrent and intractable. If diversion fails to control bleeding, resection is necessary, even if it involves an abdominoperineal resection. Therefore, conservative therapy can become radical for this supposedly benign illness.

Original languageEnglish (US)
Pages (from-to)569-572
Number of pages4
JournalSurgery Gynecology and Obstetrics
Volume142
Issue number4
StatePublished - Dec 1 1976

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Colitis
Radiotherapy
Hemorrhage
Therapeutics
Radium
Causality
Fistula
Morbidity
Wounds and Injuries
Growth
Conservative Treatment

All Science Journal Classification (ASJC) codes

  • Surgery
  • Obstetrics and Gynecology

Cite this

Smith, J. S., & Milford, H. E. (1976). Management of colitis caused by irradiation. Surgery Gynecology and Obstetrics, 142(4), 569-572.
Smith, J. Stanley ; Milford, H. E. / Management of colitis caused by irradiation. In: Surgery Gynecology and Obstetrics. 1976 ; Vol. 142, No. 4. pp. 569-572.
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Smith, JS & Milford, HE 1976, 'Management of colitis caused by irradiation', Surgery Gynecology and Obstetrics, vol. 142, no. 4, pp. 569-572.

Management of colitis caused by irradiation. / Smith, J. Stanley; Milford, H. E.

In: Surgery Gynecology and Obstetrics, Vol. 142, No. 4, 01.12.1976, p. 569-572.

Research output: Contribution to journalArticle

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AB - Radiation therapy has assumed a role of primary importance in the management of gynecologic and other malignant growths. To be effective, the treatment dosage must be adequate. However, with higher dosages for curative radiation therapy, damage from the treatment may promote prolonged morbidity and even death. The effects of this treatment may be intensified by predisposing conditions within the patient, but the damage seems to be related to the insertion of radium. Prior to therapy, each patient must be individualized, and any predisposing factors should be kept in mind during treatment to recognize and treat these complications early. Once complications have arisen, the most conservative modality of dealing with the irradiated tissue is best, since these areas of intestinal injury do not heal. This requires early diversion or resection as conservative therapy, because fistulas and bleeding will become recurrent and intractable. If diversion fails to control bleeding, resection is necessary, even if it involves an abdominoperineal resection. Therefore, conservative therapy can become radical for this supposedly benign illness.

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Smith JS, Milford HE. Management of colitis caused by irradiation. Surgery Gynecology and Obstetrics. 1976 Dec 1;142(4):569-572.