Management of Regional Metastases in Well-Differentiated Thyroid Cancer

Stuart Ort, David Goldenberg

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

Thyroid cancer represents the most common endocrine cancer, and rates have been increasing over the last 3 decades. The treatment of cervical metastases in well differentiated thyroid cancer remains in evolution. Many questions require further resolution. Unlike many other malignancies, most large studies have found that overall survival is not significantly affected by regional metastases. On the other hand, several studies have noted that regional disease may decrease survival in selected patient groups. The greatest effect of lymph node metastases seems to be an increase in recurrence rates. Except for the compartment-oriented removal of clinically positive nodes, few strong recommendations may be made.

Original languageEnglish (US)
Pages (from-to)1207-1218
Number of pages12
JournalOtolaryngologic Clinics of North America
Volume41
Issue number6
DOIs
StatePublished - Dec 1 2008

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Thyroid Neoplasms
Neoplasm Metastasis
Endocrine Gland Neoplasms
Survival
Lymph Nodes
Recurrence
Neoplasms
Therapeutics

All Science Journal Classification (ASJC) codes

  • Otorhinolaryngology

Cite this

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Management of Regional Metastases in Well-Differentiated Thyroid Cancer. / Ort, Stuart; Goldenberg, David.

In: Otolaryngologic Clinics of North America, Vol. 41, No. 6, 01.12.2008, p. 1207-1218.

Research output: Contribution to journalReview article

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AU - Goldenberg, David

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N2 - Thyroid cancer represents the most common endocrine cancer, and rates have been increasing over the last 3 decades. The treatment of cervical metastases in well differentiated thyroid cancer remains in evolution. Many questions require further resolution. Unlike many other malignancies, most large studies have found that overall survival is not significantly affected by regional metastases. On the other hand, several studies have noted that regional disease may decrease survival in selected patient groups. The greatest effect of lymph node metastases seems to be an increase in recurrence rates. Except for the compartment-oriented removal of clinically positive nodes, few strong recommendations may be made.

AB - Thyroid cancer represents the most common endocrine cancer, and rates have been increasing over the last 3 decades. The treatment of cervical metastases in well differentiated thyroid cancer remains in evolution. Many questions require further resolution. Unlike many other malignancies, most large studies have found that overall survival is not significantly affected by regional metastases. On the other hand, several studies have noted that regional disease may decrease survival in selected patient groups. The greatest effect of lymph node metastases seems to be an increase in recurrence rates. Except for the compartment-oriented removal of clinically positive nodes, few strong recommendations may be made.

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