"Marden-walker syndrome": Neuropathologic findings in two siblings

Jack N. Sees, Javad Towfighi, David B. Robins, Roger Ladda

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Neuropathologic examination of two siblings with phenotypic features consistent with Marden-Walker syndrome revealed central nervous system abnormalities which include reduction in the number of spinal anterior horn cells. The occurrence of these changes in a sibling pair provides strong evidence for a genetic etiology. The relationship between the neuropathologic changes and other phenotypic manifestations in this syndrome and in the closely related syndrome of Pena-Shokeir are discussed..

Original languageEnglish (US)
Pages (from-to)807-818
Number of pages12
JournalFetal and Pediatric Pathology
Volume10
Issue number5
DOIs
StatePublished - Jan 1 1990

Fingerprint

Anterior Horn Cells
Nervous System Malformations
Central Nervous System
Marden-Walker syndrome
Alopecia, epilepsy, pyorrhea, mental subnormality

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Pathology and Forensic Medicine

Cite this

Sees, Jack N. ; Towfighi, Javad ; Robins, David B. ; Ladda, Roger. / "Marden-walker syndrome" : Neuropathologic findings in two siblings. In: Fetal and Pediatric Pathology. 1990 ; Vol. 10, No. 5. pp. 807-818.
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"Marden-walker syndrome" : Neuropathologic findings in two siblings. / Sees, Jack N.; Towfighi, Javad; Robins, David B.; Ladda, Roger.

In: Fetal and Pediatric Pathology, Vol. 10, No. 5, 01.01.1990, p. 807-818.

Research output: Contribution to journalArticle

TY - JOUR

T1 - "Marden-walker syndrome"

T2 - Neuropathologic findings in two siblings

AU - Sees, Jack N.

AU - Towfighi, Javad

AU - Robins, David B.

AU - Ladda, Roger

PY - 1990/1/1

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N2 - Neuropathologic examination of two siblings with phenotypic features consistent with Marden-Walker syndrome revealed central nervous system abnormalities which include reduction in the number of spinal anterior horn cells. The occurrence of these changes in a sibling pair provides strong evidence for a genetic etiology. The relationship between the neuropathologic changes and other phenotypic manifestations in this syndrome and in the closely related syndrome of Pena-Shokeir are discussed..

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