Materialien und gerüste im medizinischen 3-D-druck und bioprinting im kontext der knochenregeneration

Translated title of the contribution: Materials and scaffolds in medical 3D printing and bioprinting in the context of bone regeneration

Martin Heller, Heide Katharina Bauer, Elisabeth Goetze, Matthias Gielisch, Ibrahim Tarik Ozbolat, Kazim K. Moncal, Elias Rizk, Hermann Seitz, Michael Gelinsky, Heinz C. Schröder, Xiaohong H. Wang, Werner E. Werner, Bilal Al-Nawas

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The structural and functional repair of lost bone is still one of the biggest challenges in regenerative medicine. In many cases, autologous bone is used for the reconstruction of bone tissue; however, the availability of autologous material is limited, which always means additional stress to the patient.1-3 Due to this, more and more frequently various biocompatible materials are being used instead for bone augmentation.4,5 In this context, in order to ensure the structural function of the bone, scaffolds are implanted and fixed into the bone defect, depending on the medical indication. 6 Nevertheless, for the surgeon, every individual clinical condition in which standardized scaffolds have to be aligned is challenging, and in many cases the alignment is not possible without limitations. Therefore, in the last decades, 3D printing (3DP) or additive manufacturing (AM) of scaffolds has become one of the most innovative approaches in surgery to individualize and improve the treatment of patients. Numerous biocompatible materials are available for 3DP, and various printing techniques can be applied, depending on the process conditions of these materials.7-9 Besides these conventional printing techniques, another promising approach in the context of medical AM is 3D bioprinting, a technique which makes it possible to print human cells embedded in special carrier substances to generate functional tissues.10,11 Even the direct printing into bone defects or lesions becomes possible. 3DP is already improving the treatment of patients, and has the potential to revolutionize regenerative medicine in future.

Original languageGerman
Pages (from-to)301-321
Number of pages21
JournalInternational Journal of Computerized Dentistry
Volume19
Issue number4
StatePublished - Jan 1 2016

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Bioprinting
Bone Regeneration
Bone and Bones
Printing
Regenerative Medicine
Biocompatible Materials
Three Dimensional Printing

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Heller, M., Bauer, H. K., Goetze, E., Gielisch, M., Ozbolat, I. T., Moncal, K. K., ... Al-Nawas, B. (2016). Materialien und gerüste im medizinischen 3-D-druck und bioprinting im kontext der knochenregeneration. International Journal of Computerized Dentistry, 19(4), 301-321.
Heller, Martin ; Bauer, Heide Katharina ; Goetze, Elisabeth ; Gielisch, Matthias ; Ozbolat, Ibrahim Tarik ; Moncal, Kazim K. ; Rizk, Elias ; Seitz, Hermann ; Gelinsky, Michael ; Schröder, Heinz C. ; Wang, Xiaohong H. ; Werner, Werner E. ; Al-Nawas, Bilal. / Materialien und gerüste im medizinischen 3-D-druck und bioprinting im kontext der knochenregeneration. In: International Journal of Computerized Dentistry. 2016 ; Vol. 19, No. 4. pp. 301-321.
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abstract = "The structural and functional repair of lost bone is still one of the biggest challenges in regenerative medicine. In many cases, autologous bone is used for the reconstruction of bone tissue; however, the availability of autologous material is limited, which always means additional stress to the patient.1-3 Due to this, more and more frequently various biocompatible materials are being used instead for bone augmentation.4,5 In this context, in order to ensure the structural function of the bone, scaffolds are implanted and fixed into the bone defect, depending on the medical indication. 6 Nevertheless, for the surgeon, every individual clinical condition in which standardized scaffolds have to be aligned is challenging, and in many cases the alignment is not possible without limitations. Therefore, in the last decades, 3D printing (3DP) or additive manufacturing (AM) of scaffolds has become one of the most innovative approaches in surgery to individualize and improve the treatment of patients. Numerous biocompatible materials are available for 3DP, and various printing techniques can be applied, depending on the process conditions of these materials.7-9 Besides these conventional printing techniques, another promising approach in the context of medical AM is 3D bioprinting, a technique which makes it possible to print human cells embedded in special carrier substances to generate functional tissues.10,11 Even the direct printing into bone defects or lesions becomes possible. 3DP is already improving the treatment of patients, and has the potential to revolutionize regenerative medicine in future.",
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Heller, M, Bauer, HK, Goetze, E, Gielisch, M, Ozbolat, IT, Moncal, KK, Rizk, E, Seitz, H, Gelinsky, M, Schröder, HC, Wang, XH, Werner, WE & Al-Nawas, B 2016, 'Materialien und gerüste im medizinischen 3-D-druck und bioprinting im kontext der knochenregeneration', International Journal of Computerized Dentistry, vol. 19, no. 4, pp. 301-321.

Materialien und gerüste im medizinischen 3-D-druck und bioprinting im kontext der knochenregeneration. / Heller, Martin; Bauer, Heide Katharina; Goetze, Elisabeth; Gielisch, Matthias; Ozbolat, Ibrahim Tarik; Moncal, Kazim K.; Rizk, Elias; Seitz, Hermann; Gelinsky, Michael; Schröder, Heinz C.; Wang, Xiaohong H.; Werner, Werner E.; Al-Nawas, Bilal.

In: International Journal of Computerized Dentistry, Vol. 19, No. 4, 01.01.2016, p. 301-321.

Research output: Contribution to journalArticle

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AU - Heller, Martin

AU - Bauer, Heide Katharina

AU - Goetze, Elisabeth

AU - Gielisch, Matthias

AU - Ozbolat, Ibrahim Tarik

AU - Moncal, Kazim K.

AU - Rizk, Elias

AU - Seitz, Hermann

AU - Gelinsky, Michael

AU - Schröder, Heinz C.

AU - Wang, Xiaohong H.

AU - Werner, Werner E.

AU - Al-Nawas, Bilal

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