Maternal and Paternal Infertility Disorders and Treatments and Autism Spectrum Disorder: Findings from the Study to Explore Early Development

Laura A. Schieve, Carolyn Drews-Botsch, Shericka Harris, Craig Newschaffer, Julie Daniels, Carolyn DiGuiseppi, Lisa A. Croen, Gayle C. Windham

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Previous studies of associations between ASD and conception using assisted reproductive technology (ART) are inconsistent and few studies have examined associations with other infertility treatments or infertility disorders. We examined associations between ASD and maternal/paternal infertility disorders and numerous maternal treatments among 1538 mother–child pairs in the Study to Explore Early Development, a population-based case-control study. ASD was associated with any female infertility diagnosis and several specific diagnoses: blocked tubes, endometriosis, uterine-factor infertility, and polycystic ovarian syndrome. Stratified analyses suggested associations were limited to/much stronger among second or later births. The findings were not explained by sociodemographic factors such as maternal age or education or multiple or preterm birth. ASD was not associated with ART or non-ART infertility treatments.

Original languageEnglish (US)
Pages (from-to)3994-4005
Number of pages12
JournalJournal of Autism and Developmental Disorders
Volume47
Issue number12
DOIs
StatePublished - Dec 1 2017

All Science Journal Classification (ASJC) codes

  • Developmental and Educational Psychology

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