Maternal collagen vascular disease associated with fetal heart block and degenerative changes of the atrioventricular valves

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

We report the case of a fetus diagnosed at 24 weeks' gestation with complete heart block associated with maternal collagen vascular disease and Sjögren's antibody. Serial fetal echocardiograms noted increased echogenicity along the tricuspid and mitral valves without insufficiency. Postnatally, severe tricuspid insufficiency occurred following placement of an endocardial pacing lead, and severe mitral insufficiency occurred acutely at 2.5 months of age. Both valves were noted at surgery to have fibrotic and calcific chordae tendineae that had ruptured from their papillary muscles. An inflammatory reaction within the fetal heart related to transplacental passage of Sjögren's antibody was likely responsible.

Original languageEnglish (US)
Pages (from-to)204-206
Number of pages3
JournalPediatric Cardiology
Volume15
Issue number4
DOIs
StatePublished - Jul 1 1994

Fingerprint

Fetal Heart
Collagen Diseases
Heart Block
Mitral Valve Insufficiency
Vascular Diseases
Chordae Tendineae
Mothers
Tricuspid Valve
Papillary Muscles
Antibodies
Fetus
Pregnancy
Lead

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Cardiology and Cardiovascular Medicine

Cite this

@article{f4728d95e17142d9b910f38f3963d182,
title = "Maternal collagen vascular disease associated with fetal heart block and degenerative changes of the atrioventricular valves",
abstract = "We report the case of a fetus diagnosed at 24 weeks' gestation with complete heart block associated with maternal collagen vascular disease and Sj{\"o}gren's antibody. Serial fetal echocardiograms noted increased echogenicity along the tricuspid and mitral valves without insufficiency. Postnatally, severe tricuspid insufficiency occurred following placement of an endocardial pacing lead, and severe mitral insufficiency occurred acutely at 2.5 months of age. Both valves were noted at surgery to have fibrotic and calcific chordae tendineae that had ruptured from their papillary muscles. An inflammatory reaction within the fetal heart related to transplacental passage of Sj{\"o}gren's antibody was likely responsible.",
author = "Howard Weber and John Myers",
year = "1994",
month = "7",
day = "1",
doi = "10.1007/BF00800677",
language = "English (US)",
volume = "15",
pages = "204--206",
journal = "Pediatric Cardiology",
issn = "0172-0643",
publisher = "Springer New York",
number = "4",

}

TY - JOUR

T1 - Maternal collagen vascular disease associated with fetal heart block and degenerative changes of the atrioventricular valves

AU - Weber, Howard

AU - Myers, John

PY - 1994/7/1

Y1 - 1994/7/1

N2 - We report the case of a fetus diagnosed at 24 weeks' gestation with complete heart block associated with maternal collagen vascular disease and Sjögren's antibody. Serial fetal echocardiograms noted increased echogenicity along the tricuspid and mitral valves without insufficiency. Postnatally, severe tricuspid insufficiency occurred following placement of an endocardial pacing lead, and severe mitral insufficiency occurred acutely at 2.5 months of age. Both valves were noted at surgery to have fibrotic and calcific chordae tendineae that had ruptured from their papillary muscles. An inflammatory reaction within the fetal heart related to transplacental passage of Sjögren's antibody was likely responsible.

AB - We report the case of a fetus diagnosed at 24 weeks' gestation with complete heart block associated with maternal collagen vascular disease and Sjögren's antibody. Serial fetal echocardiograms noted increased echogenicity along the tricuspid and mitral valves without insufficiency. Postnatally, severe tricuspid insufficiency occurred following placement of an endocardial pacing lead, and severe mitral insufficiency occurred acutely at 2.5 months of age. Both valves were noted at surgery to have fibrotic and calcific chordae tendineae that had ruptured from their papillary muscles. An inflammatory reaction within the fetal heart related to transplacental passage of Sjögren's antibody was likely responsible.

UR - http://www.scopus.com/inward/record.url?scp=0028308278&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028308278&partnerID=8YFLogxK

U2 - 10.1007/BF00800677

DO - 10.1007/BF00800677

M3 - Article

VL - 15

SP - 204

EP - 206

JO - Pediatric Cardiology

JF - Pediatric Cardiology

SN - 0172-0643

IS - 4

ER -