Mechanical properties of bioactive glasses, ceramics, glass-ceramics and composites: State-of-the-art review and future challenges

Gurbinder Kaur, Vishal Kumar, Francesco Baino, John Mauro, Gary Pickrell, Iain Evans, Oana Bretcanu

Research output: Contribution to journalReview article

4 Citations (Scopus)

Abstract

The repair and restoration of bone defects in orthopaedic and dental surgery remains a major challenge despite advances in surgical procedures and post-operative treatments. Bioactive glasses, ceramics, glass-ceramics and composites show considerable potential for such applications as they can promote bone tissue regeneration. This paper presents an overview of the mechanical properties of various bioactive materials, which have the potential for bone regeneration. It also identifies current strategies for improving the mechanical properties of these novel materials, as these are rarely ideal as direct replacements for human bone. For this reason bioactive organic-inorganic composites and hybrids that have tailorable mechanical properties are of particular interest. The inorganic component (bioactive glass, ceramic or glass-ceramic) can provide both strength and bioactivity, while the organic component can add structural reinforcement, toughness and processability. Another topic presented in this paper includes 3D porous scaffolds that act as a template for cell attachment, proliferation and bone growth. Mechanical limitations of existing glass and ceramic scaffolds are discussed, along with the relevant challenges and strategies for further improvement. Advantages and disadvantages of different bioactive materials are critically examined. This paper is focused on optimization of biomaterials properties, in particular mechanical properties and bioactivity.

Original languageEnglish (US)
Article number109895
JournalMaterials Science and Engineering C
Volume104
DOIs
StatePublished - Nov 1 2019

Fingerprint

Bioactive glass
Glass ceramics
activity (biology)
bones
Bone
mechanical properties
ceramics
Mechanical properties
composite materials
glass
Composite materials
Bioactivity
regeneration
Scaffolds
orthopedics
Tissue regeneration
Orthopedics
Biocompatible Materials
toughness
reinforcement

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

Cite this

Kaur, Gurbinder ; Kumar, Vishal ; Baino, Francesco ; Mauro, John ; Pickrell, Gary ; Evans, Iain ; Bretcanu, Oana. / Mechanical properties of bioactive glasses, ceramics, glass-ceramics and composites : State-of-the-art review and future challenges. In: Materials Science and Engineering C. 2019 ; Vol. 104.
@article{63bcf8ad7a744ccdacc2eb21bca79db4,
title = "Mechanical properties of bioactive glasses, ceramics, glass-ceramics and composites: State-of-the-art review and future challenges",
abstract = "The repair and restoration of bone defects in orthopaedic and dental surgery remains a major challenge despite advances in surgical procedures and post-operative treatments. Bioactive glasses, ceramics, glass-ceramics and composites show considerable potential for such applications as they can promote bone tissue regeneration. This paper presents an overview of the mechanical properties of various bioactive materials, which have the potential for bone regeneration. It also identifies current strategies for improving the mechanical properties of these novel materials, as these are rarely ideal as direct replacements for human bone. For this reason bioactive organic-inorganic composites and hybrids that have tailorable mechanical properties are of particular interest. The inorganic component (bioactive glass, ceramic or glass-ceramic) can provide both strength and bioactivity, while the organic component can add structural reinforcement, toughness and processability. Another topic presented in this paper includes 3D porous scaffolds that act as a template for cell attachment, proliferation and bone growth. Mechanical limitations of existing glass and ceramic scaffolds are discussed, along with the relevant challenges and strategies for further improvement. Advantages and disadvantages of different bioactive materials are critically examined. This paper is focused on optimization of biomaterials properties, in particular mechanical properties and bioactivity.",
author = "Gurbinder Kaur and Vishal Kumar and Francesco Baino and John Mauro and Gary Pickrell and Iain Evans and Oana Bretcanu",
year = "2019",
month = "11",
day = "1",
doi = "10.1016/j.msec.2019.109895",
language = "English (US)",
volume = "104",
journal = "Materials Science and Engineering C",
issn = "0928-4931",
publisher = "Elsevier BV",

}

Mechanical properties of bioactive glasses, ceramics, glass-ceramics and composites : State-of-the-art review and future challenges. / Kaur, Gurbinder; Kumar, Vishal; Baino, Francesco; Mauro, John; Pickrell, Gary; Evans, Iain; Bretcanu, Oana.

In: Materials Science and Engineering C, Vol. 104, 109895, 01.11.2019.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Mechanical properties of bioactive glasses, ceramics, glass-ceramics and composites

T2 - State-of-the-art review and future challenges

AU - Kaur, Gurbinder

AU - Kumar, Vishal

AU - Baino, Francesco

AU - Mauro, John

AU - Pickrell, Gary

AU - Evans, Iain

AU - Bretcanu, Oana

PY - 2019/11/1

Y1 - 2019/11/1

N2 - The repair and restoration of bone defects in orthopaedic and dental surgery remains a major challenge despite advances in surgical procedures and post-operative treatments. Bioactive glasses, ceramics, glass-ceramics and composites show considerable potential for such applications as they can promote bone tissue regeneration. This paper presents an overview of the mechanical properties of various bioactive materials, which have the potential for bone regeneration. It also identifies current strategies for improving the mechanical properties of these novel materials, as these are rarely ideal as direct replacements for human bone. For this reason bioactive organic-inorganic composites and hybrids that have tailorable mechanical properties are of particular interest. The inorganic component (bioactive glass, ceramic or glass-ceramic) can provide both strength and bioactivity, while the organic component can add structural reinforcement, toughness and processability. Another topic presented in this paper includes 3D porous scaffolds that act as a template for cell attachment, proliferation and bone growth. Mechanical limitations of existing glass and ceramic scaffolds are discussed, along with the relevant challenges and strategies for further improvement. Advantages and disadvantages of different bioactive materials are critically examined. This paper is focused on optimization of biomaterials properties, in particular mechanical properties and bioactivity.

AB - The repair and restoration of bone defects in orthopaedic and dental surgery remains a major challenge despite advances in surgical procedures and post-operative treatments. Bioactive glasses, ceramics, glass-ceramics and composites show considerable potential for such applications as they can promote bone tissue regeneration. This paper presents an overview of the mechanical properties of various bioactive materials, which have the potential for bone regeneration. It also identifies current strategies for improving the mechanical properties of these novel materials, as these are rarely ideal as direct replacements for human bone. For this reason bioactive organic-inorganic composites and hybrids that have tailorable mechanical properties are of particular interest. The inorganic component (bioactive glass, ceramic or glass-ceramic) can provide both strength and bioactivity, while the organic component can add structural reinforcement, toughness and processability. Another topic presented in this paper includes 3D porous scaffolds that act as a template for cell attachment, proliferation and bone growth. Mechanical limitations of existing glass and ceramic scaffolds are discussed, along with the relevant challenges and strategies for further improvement. Advantages and disadvantages of different bioactive materials are critically examined. This paper is focused on optimization of biomaterials properties, in particular mechanical properties and bioactivity.

UR - http://www.scopus.com/inward/record.url?scp=85067804090&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85067804090&partnerID=8YFLogxK

U2 - 10.1016/j.msec.2019.109895

DO - 10.1016/j.msec.2019.109895

M3 - Review article

C2 - 31500047

AN - SCOPUS:85067804090

VL - 104

JO - Materials Science and Engineering C

JF - Materials Science and Engineering C

SN - 0928-4931

M1 - 109895

ER -