Mechanisms determining safety and performance of brain stimulating electrodes

Dana Lynn Andre, Balaji Shanmugasundaram, Jonathan Mason, Corina Drapaca, Bruce J. Gluckman

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

Electrical current is widely used to interact with or stimulate neural systems. Current transduction from device to tissue is mediated at the electrode-tissue interface by capacitive charge and electrochemistry. This charge-passingcapacity is frequency dependent. While safety parameters have been established for high-frequencies, safety has not been fully determined for novel materials and pulse frequencies significantly lower than 100 Hz. We are explicitly interested in safety parameters and performance of charge passing at low frequencies (<<100 Hz) for neural systems. We present a visual study of pH during charge passing for electrodeposited iridium oxide electrodes. Clear reaction-diffusion waves are observed that extend many hundreds of micrometers from the electrode surface.

Original languageEnglish (US)
Title of host publicationProceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Subtitle of host publicationEngineering the Future of Biomedicine, EMBC 2009
PublisherIEEE Computer Society
Pages689-692
Number of pages4
ISBN (Print)9781424432967
DOIs
StatePublished - Jan 1 2009
Event31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009 - Minneapolis, MN, United States
Duration: Sep 2 2009Sep 6 2009

Publication series

NameProceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009

Other

Other31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009
CountryUnited States
CityMinneapolis, MN
Period9/2/099/6/09

Fingerprint

Brain
Electrodes
Safety
Tissue
Electrochemistry
Iridium
Equipment and Supplies
Oxides
iridium oxide

All Science Journal Classification (ASJC) codes

  • Cell Biology
  • Developmental Biology
  • Biomedical Engineering
  • Medicine(all)

Cite this

Andre, D. L., Shanmugasundaram, B., Mason, J., Drapaca, C., & Gluckman, B. J. (2009). Mechanisms determining safety and performance of brain stimulating electrodes. In Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009 (pp. 689-692). [5334136] (Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009). IEEE Computer Society. https://doi.org/10.1109/IEMBS.2009.5334136
Andre, Dana Lynn ; Shanmugasundaram, Balaji ; Mason, Jonathan ; Drapaca, Corina ; Gluckman, Bruce J. / Mechanisms determining safety and performance of brain stimulating electrodes. Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009. IEEE Computer Society, 2009. pp. 689-692 (Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009).
@inproceedings{2e0a1178b11c458888ddf88fc2e6441b,
title = "Mechanisms determining safety and performance of brain stimulating electrodes",
abstract = "Electrical current is widely used to interact with or stimulate neural systems. Current transduction from device to tissue is mediated at the electrode-tissue interface by capacitive charge and electrochemistry. This charge-passingcapacity is frequency dependent. While safety parameters have been established for high-frequencies, safety has not been fully determined for novel materials and pulse frequencies significantly lower than 100 Hz. We are explicitly interested in safety parameters and performance of charge passing at low frequencies (<<100 Hz) for neural systems. We present a visual study of pH during charge passing for electrodeposited iridium oxide electrodes. Clear reaction-diffusion waves are observed that extend many hundreds of micrometers from the electrode surface.",
author = "Andre, {Dana Lynn} and Balaji Shanmugasundaram and Jonathan Mason and Corina Drapaca and Gluckman, {Bruce J.}",
year = "2009",
month = "1",
day = "1",
doi = "10.1109/IEMBS.2009.5334136",
language = "English (US)",
isbn = "9781424432967",
series = "Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009",
publisher = "IEEE Computer Society",
pages = "689--692",
booktitle = "Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society",
address = "United States",

}

Andre, DL, Shanmugasundaram, B, Mason, J, Drapaca, C & Gluckman, BJ 2009, Mechanisms determining safety and performance of brain stimulating electrodes. in Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009., 5334136, Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009, IEEE Computer Society, pp. 689-692, 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009, Minneapolis, MN, United States, 9/2/09. https://doi.org/10.1109/IEMBS.2009.5334136

Mechanisms determining safety and performance of brain stimulating electrodes. / Andre, Dana Lynn; Shanmugasundaram, Balaji; Mason, Jonathan; Drapaca, Corina; Gluckman, Bruce J.

Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009. IEEE Computer Society, 2009. p. 689-692 5334136 (Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

TY - GEN

T1 - Mechanisms determining safety and performance of brain stimulating electrodes

AU - Andre, Dana Lynn

AU - Shanmugasundaram, Balaji

AU - Mason, Jonathan

AU - Drapaca, Corina

AU - Gluckman, Bruce J.

PY - 2009/1/1

Y1 - 2009/1/1

N2 - Electrical current is widely used to interact with or stimulate neural systems. Current transduction from device to tissue is mediated at the electrode-tissue interface by capacitive charge and electrochemistry. This charge-passingcapacity is frequency dependent. While safety parameters have been established for high-frequencies, safety has not been fully determined for novel materials and pulse frequencies significantly lower than 100 Hz. We are explicitly interested in safety parameters and performance of charge passing at low frequencies (<<100 Hz) for neural systems. We present a visual study of pH during charge passing for electrodeposited iridium oxide electrodes. Clear reaction-diffusion waves are observed that extend many hundreds of micrometers from the electrode surface.

AB - Electrical current is widely used to interact with or stimulate neural systems. Current transduction from device to tissue is mediated at the electrode-tissue interface by capacitive charge and electrochemistry. This charge-passingcapacity is frequency dependent. While safety parameters have been established for high-frequencies, safety has not been fully determined for novel materials and pulse frequencies significantly lower than 100 Hz. We are explicitly interested in safety parameters and performance of charge passing at low frequencies (<<100 Hz) for neural systems. We present a visual study of pH during charge passing for electrodeposited iridium oxide electrodes. Clear reaction-diffusion waves are observed that extend many hundreds of micrometers from the electrode surface.

UR - http://www.scopus.com/inward/record.url?scp=77950980018&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77950980018&partnerID=8YFLogxK

U2 - 10.1109/IEMBS.2009.5334136

DO - 10.1109/IEMBS.2009.5334136

M3 - Conference contribution

C2 - 19964485

AN - SCOPUS:77950980018

SN - 9781424432967

T3 - Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009

SP - 689

EP - 692

BT - Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society

PB - IEEE Computer Society

ER -

Andre DL, Shanmugasundaram B, Mason J, Drapaca C, Gluckman BJ. Mechanisms determining safety and performance of brain stimulating electrodes. In Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009. IEEE Computer Society. 2009. p. 689-692. 5334136. (Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009). https://doi.org/10.1109/IEMBS.2009.5334136