Mechanisms of hand motor recovery after stroke

An electrophysiologic study of central motor pathways

E. P. Bastings, G. Rapisarda, G. Pennisi, A. M. De Noordhout, M. Lenaerts, David Good, P. J. Delwaide

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Mechanisms of motor recovery after a stroke are still poorly understood. A contribution of the healthy hemisphere has been proposed based on clinical and neuroimaging data. We report our observations from a group of patients studied serially during the first two months after stroke and another group of patients studied in the chronic phase after stroke using transcranial magnetic stimulation and the MRC scale for estimation of hand motor deficit. Among the patients studied in the acute and subacute phase (n = 16), recordable motor evoked potentials (MEPs) in the affected hand after contralateral hemispheric stimulation were present in all cases who improved their hand motor score. There was a strong correlation between MEP amplitude/latency and hand motor scores at day 60. In the patients studied in the chronic phase (n = 16), MEPs after stimulation of the affected hemisphere were observed in all patients with or without recovery, although the MEP amplitude was reduced in the four patients with no hand motor improvement, and normal in all patients with motor score improvement. There was also a significant correlation between the MEP amplitude/latency and hand motor scores. An ipsilateral response after focal stimulation of the intact hemisphere was only observed in one case (who did not recover). Our data do not suggest a significant participation of the intact hemisphere or of corticoreticulospinal pathways in motor recovery after stroke. Conversely, the persistence of a functional pyramidal tract seems necessary for recovery to occur after a cortical stroke.

Original languageEnglish (US)
Pages (from-to)97-108
Number of pages12
JournalJournal of Neurologic Rehabilitation
Volume11
Issue number2
StatePublished - Jan 1 1997

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Efferent Pathways
Motor Evoked Potentials
Hand
Stroke
Pyramidal Tracts
Transcranial Magnetic Stimulation
Neuroimaging

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Bastings, E. P., Rapisarda, G., Pennisi, G., De Noordhout, A. M., Lenaerts, M., Good, D., & Delwaide, P. J. (1997). Mechanisms of hand motor recovery after stroke: An electrophysiologic study of central motor pathways. Journal of Neurologic Rehabilitation, 11(2), 97-108.
Bastings, E. P. ; Rapisarda, G. ; Pennisi, G. ; De Noordhout, A. M. ; Lenaerts, M. ; Good, David ; Delwaide, P. J. / Mechanisms of hand motor recovery after stroke : An electrophysiologic study of central motor pathways. In: Journal of Neurologic Rehabilitation. 1997 ; Vol. 11, No. 2. pp. 97-108.
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Bastings, EP, Rapisarda, G, Pennisi, G, De Noordhout, AM, Lenaerts, M, Good, D & Delwaide, PJ 1997, 'Mechanisms of hand motor recovery after stroke: An electrophysiologic study of central motor pathways', Journal of Neurologic Rehabilitation, vol. 11, no. 2, pp. 97-108.

Mechanisms of hand motor recovery after stroke : An electrophysiologic study of central motor pathways. / Bastings, E. P.; Rapisarda, G.; Pennisi, G.; De Noordhout, A. M.; Lenaerts, M.; Good, David; Delwaide, P. J.

In: Journal of Neurologic Rehabilitation, Vol. 11, No. 2, 01.01.1997, p. 97-108.

Research output: Contribution to journalArticle

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AU - Bastings, E. P.

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Bastings EP, Rapisarda G, Pennisi G, De Noordhout AM, Lenaerts M, Good D et al. Mechanisms of hand motor recovery after stroke: An electrophysiologic study of central motor pathways. Journal of Neurologic Rehabilitation. 1997 Jan 1;11(2):97-108.