The candidate gene approach has identified many causes of photoreceptor rod cell death in retinitis pigmentosa. Some mutations lead to increased cyclicGMP concentrations in rods. Rod photoreceptors are also particularly susceptible to some mutations in housekeeping genes. Although many more cases of macular degeneration than retinitis pigmentosa occur each year, there is much less known about both genetic and sporadic forms of this disease.
|Original language||English (US)|
|Number of pages||1|
|Journal||Behavioral and Brain Sciences|
|State||Published - 1995|
All Science Journal Classification (ASJC) codes
- Ecology, Evolution, Behavior and Systematics
- Neuropsychology and Physiological Psychology