Mechanisms of photoreceptor degenerations

Research output: Contribution to journalArticle

Abstract

The candidate gene approach has identified many causes of photoreceptor rod cell death in retinitis pigmentosa. Some mutations lead to increased cyclicGMP concentrations in rods. Rod photoreceptors are also particularly susceptible to some mutations in housekeeping genes. Although many more cases of macular degeneration than retinitis pigmentosa occur each year, there is much less known about both genetic and sporadic forms of this disease.

Original languageEnglish (US)
Pages (from-to)470
Number of pages1
JournalBehavioral and Brain Sciences
Volume18
Issue number3
StatePublished - 1995

Fingerprint

rods (retina)
Retinal Rod Photoreceptor Cells
Retinitis Pigmentosa
photoreceptors
mutation
Mutation
gene
Essential Genes
Macular Degeneration
Cell Death
cell death
Genes
genes

All Science Journal Classification (ASJC) codes

  • Ecology, Evolution, Behavior and Systematics
  • Neuroscience(all)
  • Psychology(all)
  • Neuropsychology and Physiological Psychology

Cite this

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title = "Mechanisms of photoreceptor degenerations",
abstract = "The candidate gene approach has identified many causes of photoreceptor rod cell death in retinitis pigmentosa. Some mutations lead to increased cyclicGMP concentrations in rods. Rod photoreceptors are also particularly susceptible to some mutations in housekeeping genes. Although many more cases of macular degeneration than retinitis pigmentosa occur each year, there is much less known about both genetic and sporadic forms of this disease.",
author = "Colin Barnstable",
year = "1995",
language = "English (US)",
volume = "18",
pages = "470",
journal = "Behavioral and Brain Sciences",
issn = "0140-525X",
publisher = "Cambridge University Press",
number = "3",

}

Mechanisms of photoreceptor degenerations. / Barnstable, Colin.

In: Behavioral and Brain Sciences, Vol. 18, No. 3, 1995, p. 470.

Research output: Contribution to journalArticle

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AB - The candidate gene approach has identified many causes of photoreceptor rod cell death in retinitis pigmentosa. Some mutations lead to increased cyclicGMP concentrations in rods. Rod photoreceptors are also particularly susceptible to some mutations in housekeeping genes. Although many more cases of macular degeneration than retinitis pigmentosa occur each year, there is much less known about both genetic and sporadic forms of this disease.

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