TY - JOUR
T1 - Mercy Pregnancy and Emotional Well-being Study (MPEWS)
T2 - Understanding maternal mental health, fetal programming and child development. Study design and cohort profile
AU - Galbally, Megan
AU - van IJzendoorn, Marinus
AU - Permezel, Michael
AU - Saffery, Richard
AU - Lappas, Martha
AU - Ryan, Joanne
AU - van Rossum, Elisabeth
AU - Johnson, Andrew R.
AU - Teti, Douglas
AU - Lewis, Andrew J.
N1 - Funding Information:
EFCvR is the recipient of a Netherlands Brain Foundation Fellowship (FS2011(1)‐12). ARJ is the recipient of an Australian Postgraduate Award.
Funding Information:
JR is the recipient of a NHMRC Early Career Research Fellowship (APP1012735).
Funding Information:
This study is supported through the 2012 National Priority Funding Round of Beyondblue in a three‐year research grant (ID 519240) and a 2015 National Health and Medical Research Council (NHMRC) project grant for five years (APP1106823). Financial support has also been obtained from the Academic Research and Development Grants, Mercy Health and the Centre for Mental Health and Well‐Being, Deakin University.
Publisher Copyright:
Copyright © 2017 John Wiley & Sons, Ltd.
PY - 2017/12
Y1 - 2017/12
N2 - Maternal mental health represents a significant global health burden. The Mercy Pregnancy and Emotional Well-being Study (MPEWS) was established to provide a comprehensive investigation of early developmental mechanisms and modifiers for maternal, fetal and child emotional well-being. MPEWS is a prospective, longitudinal study from pregnancy to 36 months postpartum that includes diagnostic measures of maternal mental health, observational measures of the mother–infant relationship, measures of child development, and repeat biological sampling. A total of 282 pregnant women were recruited in early pregnancy from the Mercy Hospital for Women in Melbourne, Australia, including 52 women on antidepressant medication, 31 non-medicated women meeting diagnostic criteria for current unipolar depression or dysthymia, and 65 women with a past history of depression. Sample recruitment characteristics included a mean age of 31 years and average gestation of 16 weeks. The MPEWS cohort was comparable to national averages for Australia on key pregnancy and birth variables. Those participants taking antidepressant medication had higher mean Edinburgh Postnatal Depression Scale (EPDS) and State Trait Anxiety Inventory (STAI) scores than the cohort as a whole but were comparable on other key variables. The MPEWS protocol provides a unique opportunity to evaluate the impact of pregnancy mental health on future maternal mental health and child development to aid the development of evidence-based interventions. The study is open for collaborative proposals via approach to the principal investigators.
AB - Maternal mental health represents a significant global health burden. The Mercy Pregnancy and Emotional Well-being Study (MPEWS) was established to provide a comprehensive investigation of early developmental mechanisms and modifiers for maternal, fetal and child emotional well-being. MPEWS is a prospective, longitudinal study from pregnancy to 36 months postpartum that includes diagnostic measures of maternal mental health, observational measures of the mother–infant relationship, measures of child development, and repeat biological sampling. A total of 282 pregnant women were recruited in early pregnancy from the Mercy Hospital for Women in Melbourne, Australia, including 52 women on antidepressant medication, 31 non-medicated women meeting diagnostic criteria for current unipolar depression or dysthymia, and 65 women with a past history of depression. Sample recruitment characteristics included a mean age of 31 years and average gestation of 16 weeks. The MPEWS cohort was comparable to national averages for Australia on key pregnancy and birth variables. Those participants taking antidepressant medication had higher mean Edinburgh Postnatal Depression Scale (EPDS) and State Trait Anxiety Inventory (STAI) scores than the cohort as a whole but were comparable on other key variables. The MPEWS protocol provides a unique opportunity to evaluate the impact of pregnancy mental health on future maternal mental health and child development to aid the development of evidence-based interventions. The study is open for collaborative proposals via approach to the principal investigators.
UR - http://www.scopus.com/inward/record.url?scp=85031738988&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85031738988&partnerID=8YFLogxK
U2 - 10.1002/mpr.1558
DO - 10.1002/mpr.1558
M3 - Article
C2 - 28120519
AN - SCOPUS:85031738988
VL - 26
JO - International Journal of Methods in Psychiatric Research
JF - International Journal of Methods in Psychiatric Research
SN - 1049-8931
IS - 4
M1 - e1558
ER -