Metabo-miR: miR-211 Regulates Mitochondrial Energy Metabolism in Vitiligo

Research output: Contribution to journalComment/debate

2 Citations (Scopus)

Abstract

The study by Sahoo et al. established miR-211 as a critical regulator of cellular metabolism in vitiligo cells. miR-211, which is expressed from the transient receptor potential melastatin 1 intronic region, regulates oxidative phosphorylation and mitochondrial energy metabolism in vitiligo. Loss of miR-211 in melanocytes was shown to alter expression patterns of newly identified target genes, and those that regulate respiratory functions in melanocytes are among them. This study highlights the importance of miR-211 for the melanocyte biology and development of vitiligo.

Original languageEnglish (US)
Pages (from-to)1828-1830
Number of pages3
JournalJournal of Investigative Dermatology
Volume137
Issue number9
DOIs
StatePublished - Sep 1 2017

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Vitiligo
Melanocytes
Metabolism
Energy Metabolism
Genes
Oxidative Phosphorylation

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Biology
  • Dermatology
  • Cell Biology

Cite this

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title = "Metabo-miR: miR-211 Regulates Mitochondrial Energy Metabolism in Vitiligo",
abstract = "The study by Sahoo et al. established miR-211 as a critical regulator of cellular metabolism in vitiligo cells. miR-211, which is expressed from the transient receptor potential melastatin 1 intronic region, regulates oxidative phosphorylation and mitochondrial energy metabolism in vitiligo. Loss of miR-211 in melanocytes was shown to alter expression patterns of newly identified target genes, and those that regulate respiratory functions in melanocytes are among them. This study highlights the importance of miR-211 for the melanocyte biology and development of vitiligo.",
author = "Vladimir Spiegelman and Irina Elcheva",
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journal = "Journal of Investigative Dermatology",
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}

Metabo-miR : miR-211 Regulates Mitochondrial Energy Metabolism in Vitiligo. / Spiegelman, Vladimir; Elcheva, Irina.

In: Journal of Investigative Dermatology, Vol. 137, No. 9, 01.09.2017, p. 1828-1830.

Research output: Contribution to journalComment/debate

TY - JOUR

T1 - Metabo-miR

T2 - miR-211 Regulates Mitochondrial Energy Metabolism in Vitiligo

AU - Spiegelman, Vladimir

AU - Elcheva, Irina

PY - 2017/9/1

Y1 - 2017/9/1

N2 - The study by Sahoo et al. established miR-211 as a critical regulator of cellular metabolism in vitiligo cells. miR-211, which is expressed from the transient receptor potential melastatin 1 intronic region, regulates oxidative phosphorylation and mitochondrial energy metabolism in vitiligo. Loss of miR-211 in melanocytes was shown to alter expression patterns of newly identified target genes, and those that regulate respiratory functions in melanocytes are among them. This study highlights the importance of miR-211 for the melanocyte biology and development of vitiligo.

AB - The study by Sahoo et al. established miR-211 as a critical regulator of cellular metabolism in vitiligo cells. miR-211, which is expressed from the transient receptor potential melastatin 1 intronic region, regulates oxidative phosphorylation and mitochondrial energy metabolism in vitiligo. Loss of miR-211 in melanocytes was shown to alter expression patterns of newly identified target genes, and those that regulate respiratory functions in melanocytes are among them. This study highlights the importance of miR-211 for the melanocyte biology and development of vitiligo.

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