Metabolic and hormonal effects of feeding chickens thyroxine and diets containing varied calorie to protein ratios

R. W. Rosebrough, J. P. McMurtry, Regina Vasilatos-Younken

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Indian River male broiler chickens, growing from 7 to 28 d of age, were fed diets containing energy to protein ratios from 43 to 106 MJ/kg of protein + 0 or 1 mg/kg thyroxine (T4) to study both the energetic and metabolic costs of lipogenesis. De novo lipid synthesis was determined in the presence and absence of ouabain (ATPase inhibitor) to estimate the energetic costs of ion pumping in explants synthesizing lipid. Growth and feed consumption increased (P<0.05) when the energy to protein ratio decreased from 106 to 71 MJ/kg protein; but, both parameters decreased as the ratio was further decreased from 53 to 43 MJ/kg of protein. A large calorie-to-protein ratio and dietary T4 depressed plasma growth hormone and insulin-like growth factor-I. A large calorie-to-protein ratio increased (P<0.05) lipogenesis and the cellular energy expended in support of Na+/K+ transport. In addition, plasma thyroid hormone ratios were changed by both energy to protein ratios and T4.

Original languageEnglish (US)
Pages (from-to)77-87
Number of pages11
JournalNutrition Research
Volume12
Issue number1
DOIs
StatePublished - Jan 1 1992

Fingerprint

Thyroxine
Chickens
Diet
Proteins
Lipogenesis
Lipids
Costs and Cost Analysis
Dietary Proteins
Ouabain
Insulin-Like Growth Factor I
Thyroid Hormones
Rivers
Growth Hormone
Adenosine Triphosphatases
Ions
Growth

All Science Journal Classification (ASJC) codes

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology
  • Nutrition and Dietetics

Cite this

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title = "Metabolic and hormonal effects of feeding chickens thyroxine and diets containing varied calorie to protein ratios",
abstract = "Indian River male broiler chickens, growing from 7 to 28 d of age, were fed diets containing energy to protein ratios from 43 to 106 MJ/kg of protein + 0 or 1 mg/kg thyroxine (T4) to study both the energetic and metabolic costs of lipogenesis. De novo lipid synthesis was determined in the presence and absence of ouabain (ATPase inhibitor) to estimate the energetic costs of ion pumping in explants synthesizing lipid. Growth and feed consumption increased (P<0.05) when the energy to protein ratio decreased from 106 to 71 MJ/kg protein; but, both parameters decreased as the ratio was further decreased from 53 to 43 MJ/kg of protein. A large calorie-to-protein ratio and dietary T4 depressed plasma growth hormone and insulin-like growth factor-I. A large calorie-to-protein ratio increased (P<0.05) lipogenesis and the cellular energy expended in support of Na+/K+ transport. In addition, plasma thyroid hormone ratios were changed by both energy to protein ratios and T4.",
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Metabolic and hormonal effects of feeding chickens thyroxine and diets containing varied calorie to protein ratios. / Rosebrough, R. W.; McMurtry, J. P.; Vasilatos-Younken, Regina.

In: Nutrition Research, Vol. 12, No. 1, 01.01.1992, p. 77-87.

Research output: Contribution to journalArticle

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