Methodological considerations for treatment trials for persons with borderline personality disorder

Mary C. Zanarini, Barbara Stanley, Donald W. Black, John C. Markowitz, Marianne Goodman, Paul Pilkonis, Thomas R. Lynch, Kenneth Levy, Peter Fonagy, Martin Bohus, Joan Farrell, Charles Sanislow

Research output: Contribution to journalReview article

28 Citations (Scopus)

Abstract

BACKGROUND: The National Institute of Mental Health convened an international group of experts to examine the conduct of treatment trials for persons with borderline personality disorder (BPD). The rapid growth of treatment research had led to the recognition that investigators face unique methodological issues with these challenging patients. METHODS: Conference members reviewed critical aspects of psychotherapy and pharmacotherapy trial design for patients with BPD. RESULTS: This article summarizes discussions held on March 17-18, 2005. CONCLUSION: This paper addresses the most pressing issues in sample selection and trial design pertaining to BPD; issues that have bedeviled both investigators submitting applications and reviewers trying to assess the merit of these grants. By disseminating this work, conference members hope to make this process more consistent and productive for all concerned.

Original languageEnglish (US)
Pages (from-to)75-83
Number of pages9
JournalAnnals of Clinical Psychiatry
Volume22
Issue number2
StatePublished - May 1 2010

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Borderline Personality Disorder
Research Personnel
National Institute of Mental Health (U.S.)
Organized Financing
Psychotherapy
Therapeutics
Drug Therapy
Growth
Research

All Science Journal Classification (ASJC) codes

  • Psychiatry and Mental health

Cite this

Zanarini, M. C., Stanley, B., Black, D. W., Markowitz, J. C., Goodman, M., Pilkonis, P., ... Sanislow, C. (2010). Methodological considerations for treatment trials for persons with borderline personality disorder. Annals of Clinical Psychiatry, 22(2), 75-83.
Zanarini, Mary C. ; Stanley, Barbara ; Black, Donald W. ; Markowitz, John C. ; Goodman, Marianne ; Pilkonis, Paul ; Lynch, Thomas R. ; Levy, Kenneth ; Fonagy, Peter ; Bohus, Martin ; Farrell, Joan ; Sanislow, Charles. / Methodological considerations for treatment trials for persons with borderline personality disorder. In: Annals of Clinical Psychiatry. 2010 ; Vol. 22, No. 2. pp. 75-83.
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Zanarini, MC, Stanley, B, Black, DW, Markowitz, JC, Goodman, M, Pilkonis, P, Lynch, TR, Levy, K, Fonagy, P, Bohus, M, Farrell, J & Sanislow, C 2010, 'Methodological considerations for treatment trials for persons with borderline personality disorder', Annals of Clinical Psychiatry, vol. 22, no. 2, pp. 75-83.

Methodological considerations for treatment trials for persons with borderline personality disorder. / Zanarini, Mary C.; Stanley, Barbara; Black, Donald W.; Markowitz, John C.; Goodman, Marianne; Pilkonis, Paul; Lynch, Thomas R.; Levy, Kenneth; Fonagy, Peter; Bohus, Martin; Farrell, Joan; Sanislow, Charles.

In: Annals of Clinical Psychiatry, Vol. 22, No. 2, 01.05.2010, p. 75-83.

Research output: Contribution to journalReview article

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Zanarini MC, Stanley B, Black DW, Markowitz JC, Goodman M, Pilkonis P et al. Methodological considerations for treatment trials for persons with borderline personality disorder. Annals of Clinical Psychiatry. 2010 May 1;22(2):75-83.