Metronidazole-induced cerebellar toxicity

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Metronidazole is a very common antibacterial and antiprotozoal with wide usage across the globe, including the least developed countries. It is generally well-tolerated with a low incidence of serious side-effects. Neurological toxicity is fairly common with this drug, however majority of these are peripheral neuropathy with very few cases of central nervous toxicity reported. We report the imaging findings in two patients with cerebellar dysfunction after Metronidazole usage. Signal changes in the dentate and red nucleus were seen on magnetic resonance imaging in these patients. Most of the cases reported in literature reported similar findings, suggesting high predilection for the dentate nucleus in metronidazole induced encephalopathy.

Original languageEnglish (US)
Article number6365
Pages (from-to)4-6
Number of pages3
JournalNeurology International
Volume8
Issue number1
DOIs
StatePublished - Apr 1 2016

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Metronidazole
Cerebellar Nuclei
Red Nucleus
Cerebellar Diseases
Brain Diseases
Peripheral Nervous System Diseases
Developing Countries
Magnetic Resonance Imaging
Incidence
Pharmaceutical Preparations

All Science Journal Classification (ASJC) codes

  • Clinical Neurology

Cite this

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Metronidazole-induced cerebellar toxicity. / Agarwal, Amit; Kanekar, Sangam; Sabat, Shyam; Thamburaj, Krishnamurthy.

In: Neurology International, Vol. 8, No. 1, 6365, 01.04.2016, p. 4-6.

Research output: Contribution to journalArticle

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