MHC polymorphism and human origins

Jan Klein, N. Takahata, F. J. Ayala

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Analysis of the major histocompatibility complex locus, which governs the recognition of self by the immune system, reveals two profound surprises concerning the evolution of humans: the immune system is much older than the species that it protects, and the ancestral population must have been large, not small. There were many Adams and Eves.

Original languageEnglish (US)
Pages (from-to)78-83+4
JournalScientific American
Volume269
Issue number6
StatePublished - Jan 1 1993

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Immune System
Major Histocompatibility Complex
Population
Protect-It

All Science Journal Classification (ASJC) codes

  • General

Cite this

Klein, J., Takahata, N., & Ayala, F. J. (1993). MHC polymorphism and human origins. Scientific American, 269(6), 78-83+4.
Klein, Jan ; Takahata, N. ; Ayala, F. J. / MHC polymorphism and human origins. In: Scientific American. 1993 ; Vol. 269, No. 6. pp. 78-83+4.
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Klein, J, Takahata, N & Ayala, FJ 1993, 'MHC polymorphism and human origins', Scientific American, vol. 269, no. 6, pp. 78-83+4.

MHC polymorphism and human origins. / Klein, Jan; Takahata, N.; Ayala, F. J.

In: Scientific American, Vol. 269, No. 6, 01.01.1993, p. 78-83+4.

Research output: Contribution to journalArticle

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Klein J, Takahata N, Ayala FJ. MHC polymorphism and human origins. Scientific American. 1993 Jan 1;269(6):78-83+4.