Mice with humanized-lungs and immune system - an idealized model for COVID-19 and other respiratory illness

Sujit Pujhari, Jason L. Rasgon

Research output: Contribution to journalEditorialpeer-review

Abstract

Lack of an appropriate animal model to study severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiological agent responsible for COVID-19 pandemic disease, represents a significant hurdle in the process of understanding disease biology and evaluating therapeutic and preventive candidates. It is time for public health agencies to revisit regulation on transplantation of human pluripotent stem cells for the possibility of the development of a humanized mice model with a humanized lung.

Original languageEnglish (US)
Pages (from-to)486-488
Number of pages3
JournalVirulence
Volume11
Issue number1
DOIs
StatePublished - Jan 1 2020

All Science Journal Classification (ASJC) codes

  • Parasitology
  • Microbiology
  • Immunology
  • Microbiology (medical)
  • Infectious Diseases

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