Abstract
A highly enantioselective oxidation of benzhydrylsulfanyl acetic acid to the corresponding (S)-sulfinyl carboxylic acid was achieved employing the fungus Beauveria bassiana in very good yield. This product was amidated using the bacteria Bacillus subtilis to afford (S)-modafinil in good yield.
Original language | English (US) |
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Pages (from-to) | 3507-3511 |
Number of pages | 5 |
Journal | Tetrahedron Asymmetry |
Volume | 16 |
Issue number | 21 |
DOIs | |
State | Published - Oct 31 2005 |
All Science Journal Classification (ASJC) codes
- Catalysis
- Physical and Theoretical Chemistry
- Organic Chemistry
- Inorganic Chemistry