Microfluidic device with carbon nanotube channel walls for blood plasma extraction

Yin Ting Yeh, Nestor Perea-Lopez, Archi Dasgupta, Ramdane Harouaka, Mauricio Terrones, Si Yang Zheng

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

The human plasma biomarker analysis is promised to be a revolution for disease diagnosis and therapeutic monitoring, but it also presents major technical challenges that needs to be addressed [1]. Plasma extract from whole blood is the first step for plasma biomarker analysis. This paper reports a new microfluidic device with channel walls made of nitrogen-doped carbon nanotubes (CNxCNT) as a point-of-care device to continuously extract plasma from human whole blood. The cross flow microfiltration principle is applied in this plasma extraction device. The blood sample is transported within the double spiral channels. The plasma diffuses through the porous CNxCNT wall into the spiral plasma channel while blood cells continue to flow inside the spiral blood sample channel [2].

Original languageEnglish (US)
Title of host publicationIEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013
Pages951-954
Number of pages4
DOIs
StatePublished - Apr 2 2013
EventIEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013 - Taipei, Taiwan, Province of China
Duration: Jan 20 2013Jan 24 2013

Publication series

NameProceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
ISSN (Print)1084-6999

Other

OtherIEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013
CountryTaiwan, Province of China
CityTaipei
Period1/20/131/24/13

Fingerprint

blood plasma
Carbon Nanotubes
microfluidic devices
Microfluidics
Carbon nanotubes
Blood
carbon nanotubes
Plasmas
blood
Biomarkers
biomarkers
Plasma (human)
porous walls
Microfiltration
blood cells
cross flow
Nitrogen
Cells
Monitoring
nitrogen

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Mechanical Engineering
  • Electrical and Electronic Engineering

Cite this

Yeh, Y. T., Perea-Lopez, N., Dasgupta, A., Harouaka, R., Terrones, M., & Zheng, S. Y. (2013). Microfluidic device with carbon nanotube channel walls for blood plasma extraction. In IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013 (pp. 951-954). [6474403] (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)). https://doi.org/10.1109/MEMSYS.2013.6474403
Yeh, Yin Ting ; Perea-Lopez, Nestor ; Dasgupta, Archi ; Harouaka, Ramdane ; Terrones, Mauricio ; Zheng, Si Yang. / Microfluidic device with carbon nanotube channel walls for blood plasma extraction. IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013. 2013. pp. 951-954 (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)).
@inproceedings{a4a10c4f347844f2b5ed88f2d0efe2c8,
title = "Microfluidic device with carbon nanotube channel walls for blood plasma extraction",
abstract = "The human plasma biomarker analysis is promised to be a revolution for disease diagnosis and therapeutic monitoring, but it also presents major technical challenges that needs to be addressed [1]. Plasma extract from whole blood is the first step for plasma biomarker analysis. This paper reports a new microfluidic device with channel walls made of nitrogen-doped carbon nanotubes (CNxCNT) as a point-of-care device to continuously extract plasma from human whole blood. The cross flow microfiltration principle is applied in this plasma extraction device. The blood sample is transported within the double spiral channels. The plasma diffuses through the porous CNxCNT wall into the spiral plasma channel while blood cells continue to flow inside the spiral blood sample channel [2].",
author = "Yeh, {Yin Ting} and Nestor Perea-Lopez and Archi Dasgupta and Ramdane Harouaka and Mauricio Terrones and Zheng, {Si Yang}",
year = "2013",
month = "4",
day = "2",
doi = "10.1109/MEMSYS.2013.6474403",
language = "English (US)",
isbn = "9781467356558",
series = "Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)",
pages = "951--954",
booktitle = "IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013",

}

Yeh, YT, Perea-Lopez, N, Dasgupta, A, Harouaka, R, Terrones, M & Zheng, SY 2013, Microfluidic device with carbon nanotube channel walls for blood plasma extraction. in IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013., 6474403, Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS), pp. 951-954, IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013, Taipei, Taiwan, Province of China, 1/20/13. https://doi.org/10.1109/MEMSYS.2013.6474403

Microfluidic device with carbon nanotube channel walls for blood plasma extraction. / Yeh, Yin Ting; Perea-Lopez, Nestor; Dasgupta, Archi; Harouaka, Ramdane; Terrones, Mauricio; Zheng, Si Yang.

IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013. 2013. p. 951-954 6474403 (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

TY - GEN

T1 - Microfluidic device with carbon nanotube channel walls for blood plasma extraction

AU - Yeh, Yin Ting

AU - Perea-Lopez, Nestor

AU - Dasgupta, Archi

AU - Harouaka, Ramdane

AU - Terrones, Mauricio

AU - Zheng, Si Yang

PY - 2013/4/2

Y1 - 2013/4/2

N2 - The human plasma biomarker analysis is promised to be a revolution for disease diagnosis and therapeutic monitoring, but it also presents major technical challenges that needs to be addressed [1]. Plasma extract from whole blood is the first step for plasma biomarker analysis. This paper reports a new microfluidic device with channel walls made of nitrogen-doped carbon nanotubes (CNxCNT) as a point-of-care device to continuously extract plasma from human whole blood. The cross flow microfiltration principle is applied in this plasma extraction device. The blood sample is transported within the double spiral channels. The plasma diffuses through the porous CNxCNT wall into the spiral plasma channel while blood cells continue to flow inside the spiral blood sample channel [2].

AB - The human plasma biomarker analysis is promised to be a revolution for disease diagnosis and therapeutic monitoring, but it also presents major technical challenges that needs to be addressed [1]. Plasma extract from whole blood is the first step for plasma biomarker analysis. This paper reports a new microfluidic device with channel walls made of nitrogen-doped carbon nanotubes (CNxCNT) as a point-of-care device to continuously extract plasma from human whole blood. The cross flow microfiltration principle is applied in this plasma extraction device. The blood sample is transported within the double spiral channels. The plasma diffuses through the porous CNxCNT wall into the spiral plasma channel while blood cells continue to flow inside the spiral blood sample channel [2].

UR - http://www.scopus.com/inward/record.url?scp=84875413536&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84875413536&partnerID=8YFLogxK

U2 - 10.1109/MEMSYS.2013.6474403

DO - 10.1109/MEMSYS.2013.6474403

M3 - Conference contribution

AN - SCOPUS:84875413536

SN - 9781467356558

T3 - Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)

SP - 951

EP - 954

BT - IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013

ER -

Yeh YT, Perea-Lopez N, Dasgupta A, Harouaka R, Terrones M, Zheng SY. Microfluidic device with carbon nanotube channel walls for blood plasma extraction. In IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013. 2013. p. 951-954. 6474403. (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)). https://doi.org/10.1109/MEMSYS.2013.6474403