Microfluidic device with carbon nanotube channel walls for blood plasma extraction

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

The human plasma biomarker analysis is promised to be a revolution for disease diagnosis and therapeutic monitoring, but it also presents major technical challenges that needs to be addressed [1]. Plasma extract from whole blood is the first step for plasma biomarker analysis. This paper reports a new microfluidic device with channel walls made of nitrogen-doped carbon nanotubes (CNxCNT) as a point-of-care device to continuously extract plasma from human whole blood. The cross flow microfiltration principle is applied in this plasma extraction device. The blood sample is transported within the double spiral channels. The plasma diffuses through the porous CNxCNT wall into the spiral plasma channel while blood cells continue to flow inside the spiral blood sample channel [2].

Original languageEnglish (US)
Title of host publicationIEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013
Pages951-954
Number of pages4
DOIs
StatePublished - Apr 2 2013
EventIEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013 - Taipei, Taiwan, Province of China
Duration: Jan 20 2013Jan 24 2013

Other

OtherIEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013
CountryTaiwan, Province of China
CityTaipei
Period1/20/131/24/13

Fingerprint

blood plasma
Carbon Nanotubes
microfluidic devices
Microfluidics
Carbon nanotubes
Blood
carbon nanotubes
Plasmas
blood
Biomarkers
biomarkers
Plasma (human)
porous walls
Microfiltration
blood cells
cross flow
Nitrogen
Cells
Monitoring
nitrogen

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Mechanical Engineering
  • Electrical and Electronic Engineering

Cite this

Yeh, Y-T., Perea Lopez, N., Dasgupta, A., Harouaka, R., Terrones Maldonado, M., & Zheng, S. (2013). Microfluidic device with carbon nanotube channel walls for blood plasma extraction. In IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013 (pp. 951-954). [6474403] https://doi.org/10.1109/MEMSYS.2013.6474403
Yeh, Yin-Ting ; Perea Lopez, Nestor ; Dasgupta, Archi ; Harouaka, Ramdane ; Terrones Maldonado, Mauricio ; Zheng, Siyang. / Microfluidic device with carbon nanotube channel walls for blood plasma extraction. IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013. 2013. pp. 951-954
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title = "Microfluidic device with carbon nanotube channel walls for blood plasma extraction",
abstract = "The human plasma biomarker analysis is promised to be a revolution for disease diagnosis and therapeutic monitoring, but it also presents major technical challenges that needs to be addressed [1]. Plasma extract from whole blood is the first step for plasma biomarker analysis. This paper reports a new microfluidic device with channel walls made of nitrogen-doped carbon nanotubes (CNxCNT) as a point-of-care device to continuously extract plasma from human whole blood. The cross flow microfiltration principle is applied in this plasma extraction device. The blood sample is transported within the double spiral channels. The plasma diffuses through the porous CNxCNT wall into the spiral plasma channel while blood cells continue to flow inside the spiral blood sample channel [2].",
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Yeh, Y-T, Perea Lopez, N, Dasgupta, A, Harouaka, R, Terrones Maldonado, M & Zheng, S 2013, Microfluidic device with carbon nanotube channel walls for blood plasma extraction. in IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013., 6474403, pp. 951-954, IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013, Taipei, Taiwan, Province of China, 1/20/13. https://doi.org/10.1109/MEMSYS.2013.6474403

Microfluidic device with carbon nanotube channel walls for blood plasma extraction. / Yeh, Yin-Ting; Perea Lopez, Nestor; Dasgupta, Archi; Harouaka, Ramdane; Terrones Maldonado, Mauricio; Zheng, Siyang.

IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013. 2013. p. 951-954 6474403.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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AB - The human plasma biomarker analysis is promised to be a revolution for disease diagnosis and therapeutic monitoring, but it also presents major technical challenges that needs to be addressed [1]. Plasma extract from whole blood is the first step for plasma biomarker analysis. This paper reports a new microfluidic device with channel walls made of nitrogen-doped carbon nanotubes (CNxCNT) as a point-of-care device to continuously extract plasma from human whole blood. The cross flow microfiltration principle is applied in this plasma extraction device. The blood sample is transported within the double spiral channels. The plasma diffuses through the porous CNxCNT wall into the spiral plasma channel while blood cells continue to flow inside the spiral blood sample channel [2].

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Yeh Y-T, Perea Lopez N, Dasgupta A, Harouaka R, Terrones Maldonado M, Zheng S. Microfluidic device with carbon nanotube channel walls for blood plasma extraction. In IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013. 2013. p. 951-954. 6474403 https://doi.org/10.1109/MEMSYS.2013.6474403