MicroRNA expression altered by diet: Can food be medicinal?

Joshua D. Palmer, Benjamin P. Soule, Brittany A. Simone, Nicholas G. Zaorsky, Lianjin Jin, Nicole L. Simone

Research output: Contribution to journalReview articlepeer-review

50 Scopus citations

Abstract

As the link between metabolism and major disease processes becomes more well-defined, the identification of key molecular targets is leading to new therapeutic strategies. As a result, small non-coding RNA molecules that regulate gene expression via epigenetic alterations, microRNAs have been identified as regulators of these metabolic processes. In the last decade, dietary interventions have been used to change metabolism and to potentially alter disease progression and clinical outcomes. These interventions have been linked, at a molecular level, to microRNAs. This review will summarize the role of various dietary strategies on the expression of several microRNA families.

Original languageEnglish (US)
Pages (from-to)16-24
Number of pages9
JournalAgeing Research Reviews
Volume17
DOIs
StatePublished - Sep 2014

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Biochemistry
  • Aging
  • Molecular Biology
  • Neurology

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