Mitigation of Obesity-Promoted Diseases by Nigella sativa and Thymoquinone

Jairam K.P. Vanamala, Andrew C. Kester, Adam L. Heuberger, Lavanya Reddivari

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Obesity is closely associated with increased incidence of cardiovascular diseases, cancer, insulin resistance, and immune dysfunction, and thus obesity-mitigation strategies should take into account these secondary pathologies in addition to promoting weight loss. Recent studies indicate that black cumin (Nigella sativa) has cardio-protective, anti-cancer, anti-diabetic, antioxidant, and immune-modulatory properties. While black cumin and/or its major bioactive constituent, thymoquinone have demonstrated bioactivity in a variety of disease models, the mechanisms of action are largely unknown. Given the growing interest in and the use of functional foods and nutraceuticals, as well as the increase in obesity and chronic diseases worldwide, further research into the therapeutic/preventive effects of black cumin may be beneficial.

Original languageEnglish (US)
Pages (from-to)111-119
Number of pages9
JournalPlant Foods for Human Nutrition
Volume67
Issue number2
DOIs
StatePublished - Jun 1 2012

Fingerprint

Nigella sativa
obesity
Obesity
functional foods
Pathology
Bioactivity
Functional Food
neoplasms
disease models
Therapeutic Uses
Dietary Supplements
Antioxidants
chronic diseases
insulin resistance
Insulin
cardiovascular diseases
Insulin Resistance
Weight Loss
mechanism of action
Neoplasms

All Science Journal Classification (ASJC) codes

  • Food Science
  • Chemistry (miscellaneous)

Cite this

Vanamala, Jairam K.P. ; Kester, Andrew C. ; Heuberger, Adam L. ; Reddivari, Lavanya. / Mitigation of Obesity-Promoted Diseases by Nigella sativa and Thymoquinone. In: Plant Foods for Human Nutrition. 2012 ; Vol. 67, No. 2. pp. 111-119.
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Mitigation of Obesity-Promoted Diseases by Nigella sativa and Thymoquinone. / Vanamala, Jairam K.P.; Kester, Andrew C.; Heuberger, Adam L.; Reddivari, Lavanya.

In: Plant Foods for Human Nutrition, Vol. 67, No. 2, 01.06.2012, p. 111-119.

Research output: Contribution to journalArticle

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